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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
17.27
Human Site:
S169
Identified Species:
31.67
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S169
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
S161
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
K
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
S161
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
K
Dog
Lupus familis
XP_852829
541
60303
F99
L
Q
D
T
K
P
T
F
E
M
Q
Q
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S169
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
Rat
Rattus norvegicus
Q6AZ28
572
63413
F130
L
Q
D
T
K
P
T
F
E
M
Q
Q
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S169
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
Chicken
Gallus gallus
NP_001025797
622
68442
S169
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Q
E
Frog
Xenopus laevis
NP_001084972
584
64427
V141
L
S
P
P
I
P
P
V
H
P
D
V
H
L
K
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
A168
P
S
S
L
G
A
H
A
V
Q
R
F
H
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
D252
P
V
E
L
H
S
S
D
S
P
T
L
K
Q
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
L186
H
P
L
S
P
V
R
L
T
A
T
T
I
P
N
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
A168
P
I
V
Q
I
P
D
A
N
K
K
L
K
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
6.6
N.A.
100
100
0
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
40
40
26.6
N.A.
100
26.6
N.A.
100
100
13.3
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
16
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
8
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
16
0
0
0
0
16
39
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
24
31
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
8
0
8
0
8
0
0
0
16
0
0
% H
% Ile:
0
8
0
0
16
0
0
0
16
31
0
0
8
0
0
% I
% Lys:
31
0
0
0
16
0
0
0
0
8
8
0
16
0
24
% K
% Leu:
24
0
8
31
31
0
0
8
0
0
0
16
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% N
% Pro:
39
39
8
8
8
31
8
0
0
16
0
0
16
8
16
% P
% Gln:
0
16
0
8
0
16
31
0
0
24
47
16
16
47
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
24
31
0
0
0
% R
% Ser:
0
16
24
39
0
8
24
47
39
0
0
0
0
16
8
% S
% Thr:
0
16
31
16
0
0
16
0
8
0
16
8
0
0
8
% T
% Val:
0
8
8
0
16
39
0
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _