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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
14.55
Human Site:
S108
Identified Species:
26.67
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S108
I
H
S
L
P
S
T
S
V
T
P
H
S
P
S
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
H103
P
S
T
S
V
T
P
H
S
P
S
S
P
V
G
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
H103
P
S
T
S
V
T
P
H
S
P
S
S
P
V
G
Dog
Lupus familis
XP_852829
541
60303
S41
H
L
L
K
S
G
C
S
P
A
V
Q
I
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S108
I
H
S
L
P
S
T
S
I
T
P
H
S
P
S
Rat
Rattus norvegicus
Q6AZ28
572
63413
L72
Y
P
R
T
L
E
G
L
S
D
L
S
T
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S108
I
H
S
L
P
S
T
S
V
T
P
Q
S
P
S
Chicken
Gallus gallus
NP_001025797
622
68442
S108
I
H
P
L
P
S
T
S
V
T
P
Q
S
P
S
Frog
Xenopus laevis
NP_001084972
584
64427
F83
S
P
I
R
S
N
V
F
N
L
D
S
S
S
P
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
V108
L
P
T
G
H
S
D
V
L
Q
Q
R
Q
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
A189
R
Y
G
A
P
A
A
A
A
A
T
N
A
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
S120
V
R
C
V
C
G
N
S
L
E
T
D
S
M
I
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
L107
K
V
R
I
N
S
S
L
P
K
Y
S
T
L
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
93.3
0
N.A.
93.3
86.6
6.6
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
13.3
6.6
N.A.
100
6.6
N.A.
93.3
86.6
13.3
33.3
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
8
8
16
0
0
8
0
0
% A
% Cys:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
16
8
0
0
0
0
0
0
0
16
% G
% His:
8
31
0
0
8
0
0
16
0
0
0
16
0
0
0
% H
% Ile:
31
0
8
8
0
0
0
0
8
0
0
0
8
8
16
% I
% Lys:
8
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% K
% Leu:
8
8
8
31
8
0
0
16
16
8
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
8
8
0
8
0
0
8
0
0
0
% N
% Pro:
16
24
8
0
39
0
16
0
16
16
31
0
16
39
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
24
8
0
0
% Q
% Arg:
8
8
16
8
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
16
24
16
16
47
8
47
24
0
16
39
47
8
39
% S
% Thr:
0
0
24
8
0
16
31
0
0
31
16
0
16
0
0
% T
% Val:
8
8
0
8
16
0
8
8
24
0
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _