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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
13.64
Human Site:
S497
Identified Species:
30
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S497
L
N
N
K
G
I
L
S
L
P
H
Q
A
S
P
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S612
L
N
N
K
G
I
L
S
L
P
H
Q
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
L489
N
N
K
G
I
L
S
L
P
H
Q
A
S
P
V
Dog
Lupus familis
XP_535524
651
71773
S497
L
N
N
K
G
I
L
S
L
P
H
Q
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S497
L
S
N
K
G
I
L
S
L
P
H
Q
A
S
P
Rat
Rattus norvegicus
O70260
628
68345
I475
C
P
V
T
S
A
A
I
P
A
L
P
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
G596
A
S
P
L
N
N
K
G
I
L
N
L
P
H
Q
Chicken
Gallus gallus
NP_001026627
564
62782
G411
E
I
Q
F
K
E
D
G
S
W
A
P
M
R
S
Frog
Xenopus laevis
NP_001079161
649
71676
L496
P
L
S
N
K
S
M
L
N
L
Q
H
Q
A
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
A590
P
G
R
H
T
A
S
A
E
L
A
A
Q
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
N525
T
N
G
L
S
S
S
N
R
Q
E
K
V
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
6.6
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
6.6
N.A.
20
0
20
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
19
10
10
0
10
19
19
37
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
37
0
0
19
0
0
0
0
10
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
10
37
10
0
10
0
% H
% Ile:
0
10
0
0
10
37
0
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
37
19
0
10
0
0
0
0
10
0
10
10
% K
% Leu:
37
10
0
19
0
10
37
19
37
28
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
10
46
37
10
10
10
0
10
10
0
10
0
0
0
0
% N
% Pro:
19
10
10
0
0
0
0
0
19
37
0
19
10
10
37
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
19
37
19
0
10
% Q
% Arg:
0
0
10
0
0
0
0
0
10
0
0
0
0
10
0
% R
% Ser:
0
19
10
0
19
19
28
37
10
0
0
0
10
46
19
% S
% Thr:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _