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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYSF All Species: 4.24
Human Site: Y741 Identified Species: 18.67
UniProt: O75923 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75923 NP_001123927.1 2080 237295 Y741 T H L D Q Y L Y Q L R T H H L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540237 2083 237082 Y744 T H L D R H L Y R L R T R H L
Cat Felis silvestris
Mouse Mus musculus Q9ESD7 2090 237892 L751 T H L D Q Y L L R L R T R H L
Rat Rattus norvegicus Q9ERC5 1993 226321 G691 Q N S S D D E G D E A G D L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPC5 1992 226210 D687 S E E E A E D D G D L T S V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17388 2034 235223 D755 G L A L K W K D E A D I Y D G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.4 N.A. 93.3 30 N.A. N.A. N.A. N.A. 29.5 N.A. N.A. N.A. 26.2 N.A.
Protein Similarity: 100 N.A. N.A. 97 N.A. 96.5 48.5 N.A. N.A. N.A. N.A. 48.6 N.A. N.A. N.A. 45.9 N.A.
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 80 0 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 86.6 6.6 N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 17 0 0 0 0 17 17 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 17 17 17 34 17 17 17 0 17 17 0 % D
% Glu: 0 17 17 17 0 17 17 0 17 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 0 0 17 17 0 0 17 0 0 17 % G
% His: 0 50 0 0 0 17 0 0 0 0 0 0 17 50 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % I
% Lys: 0 0 0 0 17 0 17 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 50 17 0 0 50 17 0 50 17 0 0 17 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 17 0 0 0 34 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 0 0 0 34 0 50 0 34 0 0 % R
% Ser: 17 0 17 17 0 0 0 0 0 0 0 0 17 0 0 % S
% Thr: 50 0 0 0 0 0 0 0 0 0 0 67 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 34 0 34 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _