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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCO1
All Species:
39.09
Human Site:
Y276
Identified Species:
66.15
UniProt:
O75880
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75880
NP_004580.1
301
33814
Y276
P
D
G
E
F
L
D
Y
F
G
Q
N
K
R
K
Chimpanzee
Pan troglodytes
XP_001164786
301
33690
Y276
P
D
G
E
F
L
D
Y
F
G
Q
N
K
R
K
Rhesus Macaque
Macaca mulatta
XP_001118271
301
33849
Y276
P
D
G
E
F
L
D
Y
F
G
Q
N
K
R
K
Dog
Lupus familis
XP_546624
394
43433
Y369
P
D
G
Q
F
L
D
Y
F
G
Q
N
K
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUC9
284
31599
Y259
P
D
G
E
F
L
D
Y
F
G
Q
N
K
K
K
Rat
Rattus norvegicus
NP_001166845
284
31750
Y259
P
D
G
E
F
L
D
Y
F
G
Q
N
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423738
161
18098
F137
I
D
Q
V
A
K
A
F
R
V
Y
Y
S
E
G
Frog
Xenopus laevis
NP_001108271
275
31026
Y249
P
D
G
L
F
T
D
Y
Y
G
R
G
K
T
D
Zebra Danio
Brachydanio rerio
Q5RH02
279
32092
Y252
P
D
G
L
F
I
D
Y
Y
N
R
M
K
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608884
251
28157
Y220
P
D
G
E
F
V
D
Y
Y
G
Q
N
R
D
K
Honey Bee
Apis mellifera
XP_001122061
262
30294
Y221
P
D
G
L
F
V
D
Y
Y
G
L
T
H
T
A
Nematode Worm
Caenorhab. elegans
NP_494755
312
35631
H277
I
D
P
S
G
Q
F
H
D
Y
Y
G
Q
N
R
Sea Urchin
Strong. purpuratus
XP_797763
313
34510
Y285
P
D
G
S
F
I
D
Y
Y
G
Q
N
K
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23833
295
33147
D254
D
P
E
G
Q
F
V
D
A
L
G
R
N
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
94.3
59.6
N.A.
70.4
69
N.A.
N.A.
41.5
40.2
41.2
N.A.
45.8
39.8
34.9
45.6
Protein Similarity:
100
99
96
64.9
N.A.
77
76.4
N.A.
N.A.
48.8
55.1
57.8
N.A.
61.4
60.4
55.1
61.9
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
N.A.
6.6
53.3
46.6
N.A.
73.3
46.6
6.6
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
13.3
66.6
66.6
N.A.
93.3
60
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
93
0
0
0
0
79
8
8
0
0
0
0
8
29
% D
% Glu:
0
0
8
43
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
79
8
8
8
43
0
0
0
0
0
0
% F
% Gly:
0
0
79
8
8
0
0
0
0
72
8
15
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
15
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
65
22
43
% K
% Leu:
0
0
0
22
0
43
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
58
8
15
8
% N
% Pro:
79
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
8
8
8
0
0
0
0
58
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
15
8
8
22
8
% R
% Ser:
0
0
0
15
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
8
0
22
0
% T
% Val:
0
0
0
8
0
15
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
36
8
15
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _