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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCO1
All Species:
44.85
Human Site:
Y256
Identified Species:
75.9
UniProt:
O75880
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75880
NP_004580.1
301
33814
Y256
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Chimpanzee
Pan troglodytes
XP_001164786
301
33690
Y256
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Rhesus Macaque
Macaca mulatta
XP_001118271
301
33849
Y256
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Dog
Lupus familis
XP_546624
394
43433
Y349
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUC9
284
31599
Y239
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Rat
Rattus norvegicus
NP_001166845
284
31750
Y239
P
K
D
E
D
E
D
Y
I
V
D
H
T
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423738
161
18098
S117
A
R
Y
V
K
E
F
S
P
K
L
V
G
L
T
Frog
Xenopus laevis
NP_001108271
275
31026
Y229
P
K
D
E
D
N
D
Y
I
L
D
H
T
I
I
Zebra Danio
Brachydanio rerio
Q5RH02
279
32092
Y232
P
K
D
E
D
G
D
Y
I
V
D
H
S
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608884
251
28157
Y200
P
R
D
E
D
N
D
Y
I
V
D
H
T
I
I
Honey Bee
Apis mellifera
XP_001122061
262
30294
Y201
P
K
D
Q
D
S
D
Y
I
V
D
H
T
I
I
Nematode Worm
Caenorhab. elegans
NP_494755
312
35631
D257
P
R
T
N
K
Q
E
D
D
Y
I
V
D
H
T
Sea Urchin
Strong. purpuratus
XP_797763
313
34510
Y265
P
K
D
E
D
N
D
Y
I
V
D
H
T
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23833
295
33147
D234
P
N
V
K
P
G
Q
D
Y
L
V
D
H
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
94.3
59.6
N.A.
70.4
69
N.A.
N.A.
41.5
40.2
41.2
N.A.
45.8
39.8
34.9
45.6
Protein Similarity:
100
99
96
64.9
N.A.
77
76.4
N.A.
N.A.
48.8
55.1
57.8
N.A.
61.4
60.4
55.1
61.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
86.6
80
N.A.
86.6
86.6
6.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
93.3
93.3
N.A.
93.3
93.3
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
79
0
79
0
79
15
8
0
79
8
8
0
0
% D
% Glu:
0
0
0
72
0
50
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
79
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
79
0
8
0
0
79
79
% I
% Lys:
0
72
0
8
15
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
22
0
0
0
0
0
0
0
0
0
% N
% Pro:
93
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
0
0
0
0
8
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
72
0
15
% T
% Val:
0
0
8
8
0
0
0
0
0
72
8
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
79
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _