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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCO1
All Species:
8.48
Human Site:
S68
Identified Species:
14.36
UniProt:
O75880
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75880
NP_004580.1
301
33814
S68
C
L
G
T
R
P
L
S
T
A
R
P
P
P
P
Chimpanzee
Pan troglodytes
XP_001164786
301
33690
S68
C
L
G
T
R
P
L
S
T
A
R
P
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001118271
301
33849
A68
G
T
R
P
L
S
T
A
R
P
P
P
P
P
P
Dog
Lupus familis
XP_546624
394
43433
P161
R
R
V
S
T
A
M
P
P
P
P
G
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUC9
284
31599
G51
R
S
R
A
F
S
A
G
P
P
P
P
G
A
G
Rat
Rattus norvegicus
NP_001166845
284
31750
R51
G
S
R
N
F
S
A
R
P
P
P
P
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423738
161
18098
Frog
Xenopus laevis
NP_001108271
275
31026
S40
L
S
R
H
V
P
Q
S
K
S
F
S
I
S
S
Zebra Danio
Brachydanio rerio
Q5RH02
279
32092
S37
I
P
N
T
T
C
R
S
S
A
P
P
H
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608884
251
28157
I37
S
T
K
G
K
G
P
I
S
W
R
S
L
A
V
Honey Bee
Apis mellifera
XP_001122061
262
30294
S37
D
R
K
G
N
R
K
S
F
I
T
W
K
S
V
Nematode Worm
Caenorhab. elegans
NP_494755
312
35631
E69
E
T
T
S
S
P
K
E
P
P
V
D
K
N
F
Sea Urchin
Strong. purpuratus
XP_797763
313
34510
Y77
T
S
V
S
Q
S
P
Y
P
Q
H
V
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23833
295
33147
T56
S
R
V
P
V
G
G
T
P
I
K
D
N
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
94.3
59.6
N.A.
70.4
69
N.A.
N.A.
41.5
40.2
41.2
N.A.
45.8
39.8
34.9
45.6
Protein Similarity:
100
99
96
64.9
N.A.
77
76.4
N.A.
N.A.
48.8
55.1
57.8
N.A.
61.4
60.4
55.1
61.9
P-Site Identity:
100
100
26.6
0
N.A.
6.6
6.6
N.A.
N.A.
0
13.3
26.6
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
33.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
0
20
33.3
N.A.
20
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
15
8
0
22
0
0
0
22
0
% A
% Cys:
15
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
8
0
8
0
0
0
8
% F
% Gly:
15
0
15
15
0
15
8
8
0
0
0
8
15
8
22
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
15
0
0
8
0
0
% I
% Lys:
0
0
15
0
8
0
15
0
8
0
8
0
15
0
8
% K
% Leu:
8
15
0
0
8
0
15
0
0
0
0
0
15
15
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
8
0
15
0
29
15
8
43
36
36
43
22
22
22
% P
% Gln:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% Q
% Arg:
15
22
29
0
15
8
8
8
8
0
22
0
0
0
8
% R
% Ser:
15
29
0
22
8
29
0
36
15
8
0
15
8
22
8
% S
% Thr:
8
22
8
22
15
0
8
8
15
0
8
0
0
0
0
% T
% Val:
0
0
22
0
15
0
0
0
0
0
8
8
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _