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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
30.91
Human Site:
T227
Identified Species:
45.33
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
T227
A
P
L
F
D
K
F
T
P
L
P
E
G
K
L
Chimpanzee
Pan troglodytes
XP_513352
475
54806
T227
A
P
L
F
D
K
F
T
P
L
P
E
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
T227
A
P
L
F
D
K
F
T
P
L
P
E
G
K
L
Dog
Lupus familis
XP_539577
422
48642
S211
G
S
K
R
S
S
H
S
N
A
Y
F
Y
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
T227
A
P
L
F
D
K
F
T
P
L
P
E
G
K
L
Rat
Rattus norvegicus
NP_001101444
475
54829
T227
A
P
L
F
D
K
F
T
P
L
P
E
G
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
I225
A
P
L
F
D
K
F
I
P
L
P
E
G
E
L
Frog
Xenopus laevis
NP_001087923
465
53504
T222
A
P
L
F
D
K
F
T
P
L
S
E
G
D
L
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
T222
A
P
L
F
D
K
F
T
P
L
P
D
G
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
E221
F
D
K
Y
T
P
L
E
K
G
A
L
R
Q
S
Honey Bee
Apis mellifera
XP_623864
433
51054
L222
I
F
D
K
Y
T
P
L
P
N
G
D
L
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
L200
L
R
T
K
I
E
E
L
A
K
S
I
D
F
P
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
P213
P
L
F
N
K
F
T
P
L
P
E
G
E
L
R
Maize
Zea mays
NP_001131195
425
48732
L214
L
F
N
K
F
T
P
L
P
E
G
V
L
R
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
P213
P
L
F
N
K
F
T
P
L
P
D
G
D
L
R
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
T225
M
P
M
F
N
K
F
T
P
L
E
D
G
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
86.6
100
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
0
6.6
N.A.
0
60
N.A.
P-Site Similarity:
0
13.3
N.A.
0
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
0
7
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
50
0
0
0
0
0
7
19
13
7
0
% D
% Glu:
0
0
0
0
0
7
7
7
0
7
13
44
7
19
7
% E
% Phe:
7
13
13
57
7
13
57
0
0
0
0
7
0
7
7
% F
% Gly:
7
0
0
0
0
0
0
0
0
7
13
13
57
7
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% I
% Lys:
0
0
13
19
13
57
0
0
7
7
0
0
0
38
0
% K
% Leu:
13
13
50
0
0
0
7
19
13
57
0
7
13
13
57
% L
% Met:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
13
7
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
13
57
0
0
0
7
13
13
69
13
44
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
0
0
7
7
13
% R
% Ser:
0
7
0
0
7
7
0
7
0
0
13
0
0
0
7
% S
% Thr:
0
0
7
0
7
13
13
50
0
0
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _