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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
10.91
Human Site:
Y287
Identified Species:
18.46
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
Y287
R
P
R
S
S
H
R
Y
F
L
E
R
G
L
E
Chimpanzee
Pan troglodytes
XP_512415
299
33388
Y287
R
P
R
S
S
H
R
Y
F
L
E
R
G
L
E
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
Y288
R
P
R
T
S
H
R
Y
F
L
E
R
G
L
E
Dog
Lupus familis
XP_542041
299
33429
F288
P
R
L
P
H
R
Y
F
Q
E
R
G
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
R288
C
R
P
Q
A
P
H
R
Y
F
Q
E
R
G
L
Rat
Rattus norvegicus
Q5U209
301
33267
K288
C
R
P
Q
V
S
H
K
Y
F
Q
E
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
H288
N
K
P
S
E
L
T
H
T
R
D
I
H
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
C333
G
E
I
I
R
E
E
C
R
F
F
K
Q
R
H
Honey Bee
Apis mellifera
XP_396289
317
35722
H303
F
K
S
Q
K
K
R
H
Q
F
F
T
E
R
C
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
Y285
V
V
P
K
R
N
V
Y
F
K
E
R
H
M
S
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
Q311
D
A
R
Q
K
K
H
Q
F
F
N
E
R
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
K279
E
E
I
E
S
S
G
K
G
R
C
K
F
L
Q
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
P293
Q
L
Q
M
V
A
K
P
V
R
R
K
R
L
R
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
G305
E
V
D
V
D
D
L
G
T
W
F
G
A
P
A
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
93.3
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
6.6
26.6
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
6.6
13.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
0
0
0
0
0
8
0
8
% A
% Cys:
15
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% C
% Asp:
8
0
8
0
8
8
0
0
0
0
8
0
0
8
0
% D
% Glu:
15
15
0
8
8
8
8
0
0
8
29
22
8
8
22
% E
% Phe:
8
0
0
0
0
0
0
8
36
36
22
0
8
0
8
% F
% Gly:
8
0
0
0
0
0
8
8
8
0
0
15
22
15
0
% G
% His:
0
0
0
0
8
22
22
15
0
0
0
0
15
0
8
% H
% Ile:
0
0
15
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
15
0
8
15
15
8
15
0
8
0
22
0
0
0
% K
% Leu:
0
8
8
0
0
8
8
0
0
22
0
0
8
36
22
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
22
29
8
0
8
0
8
0
0
0
0
0
8
0
% P
% Gln:
8
0
8
29
0
0
0
8
15
0
15
0
8
0
8
% Q
% Arg:
22
22
29
0
15
8
29
8
8
22
15
29
29
22
8
% R
% Ser:
0
0
8
22
29
15
0
0
0
0
0
0
0
0
15
% S
% Thr:
0
0
0
8
0
0
8
0
15
0
0
8
0
0
0
% T
% Val:
8
15
0
8
15
0
8
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
29
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _