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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
8.79
Human Site:
S68
Identified Species:
14.87
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.62
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
S68
E
A
L
K
V
A
D
S
K
T
L
L
E
S
E
Chimpanzee
Pan troglodytes
XP_512415
299
33388
S68
E
A
L
K
V
A
D
S
K
T
L
L
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
K69
A
L
K
V
A
D
S
K
T
L
L
E
S
E
R
Dog
Lupus familis
XP_542041
299
33429
K69
A
L
K
V
A
D
S
K
T
L
S
E
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
K69
A
L
K
V
A
D
S
K
T
L
T
E
N
E
R
Rat
Rattus norvegicus
Q5U209
301
33267
K69
A
L
K
V
A
D
S
K
T
L
T
E
N
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
K69
N
L
K
V
A
D
S
K
T
L
T
E
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
T114
C
A
D
S
K
Q
L
T
E
G
K
R
D
I
I
Honey Bee
Apis mellifera
XP_396289
317
35722
K86
D
L
G
C
A
D
S
K
S
L
T
E
E
K
R
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
N65
V
D
D
S
K
A
L
N
E
A
K
R
E
E
I
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
K92
E
L
G
F
A
D
S
K
T
L
N
E
G
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
S54
A
S
L
H
F
A
D
S
K
T
L
K
E
E
K
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
I82
S
K
K
L
T
D
P
I
R
R
M
L
F
S
K
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
R93
K
V
L
T
P
A
V
R
L
S
L
M
K
E
L
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
6.6
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
6.6
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
26.6
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
22
0
0
50
36
0
0
0
8
0
0
8
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
15
0
0
58
22
0
0
0
0
0
8
0
0
% D
% Glu:
22
0
0
0
0
0
0
0
15
0
0
50
36
58
15
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
15
% I
% Lys:
8
8
43
15
15
0
0
50
22
0
15
8
8
8
15
% K
% Leu:
0
50
29
8
0
0
15
0
8
50
36
22
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
8
0
15
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
8
0
15
0
0
50
% R
% Ser:
8
8
0
15
0
0
50
22
8
8
8
0
15
22
0
% S
% Thr:
0
0
0
8
8
0
0
8
43
22
29
0
0
0
0
% T
% Val:
8
8
0
36
15
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _