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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
49.09
Human Site:
S208
Identified Species:
83.08
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
S208
D
L
D
T
D
Y
G
S
G
Y
P
N
D
P
K
Chimpanzee
Pan troglodytes
XP_512415
299
33388
S208
D
S
D
T
D
Y
G
S
G
Y
P
N
D
P
K
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
S209
D
S
D
T
D
Y
G
S
G
Y
P
N
D
P
K
Dog
Lupus familis
XP_542041
299
33429
S209
D
L
D
A
D
Y
G
S
G
Y
P
N
D
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
S209
D
L
D
S
D
Y
G
S
G
Y
P
N
D
P
K
Rat
Rattus norvegicus
Q5U209
301
33267
S209
G
L
D
S
D
Y
G
S
G
Y
P
N
D
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
S209
D
V
D
T
D
Y
G
S
G
Y
P
N
D
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
S254
I
K
D
N
E
F
G
S
G
Y
P
G
D
P
V
Honey Bee
Apis mellifera
XP_396289
317
35722
S224
S
I
T
T
E
Y
G
S
G
Y
P
N
D
P
E
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
S206
V
P
D
A
G
Y
G
S
G
Y
P
G
D
P
N
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
S232
I
D
K
E
N
Y
G
S
G
Y
P
S
D
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
S194
D
I
N
R
N
F
G
S
G
Y
P
G
D
P
E
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
S217
D
P
D
E
I
L
G
S
G
Y
P
S
D
P
K
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
S228
D
R
T
M
A
W
G
S
G
Y
P
S
D
S
K
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
53.3
66.6
60
53.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
100
N.A.
66.6
86.6
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
53.3
66.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
8
72
0
50
0
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
0
15
15
0
0
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
100
0
100
0
0
22
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
65
% K
% Leu:
0
29
0
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
15
0
0
0
0
0
0
58
0
0
8
% N
% Pro:
0
15
0
0
0
0
0
0
0
0
100
0
0
93
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
15
0
15
0
0
0
100
0
0
0
22
0
8
0
% S
% Thr:
0
0
15
36
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
72
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _