KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIPRL
All Species:
30
Human Site:
Y202
Identified Species:
50.77
UniProt:
O75663
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75663
NP_001026970.1
272
31444
Y202
R
M
N
D
T
R
L
Y
H
E
A
D
K
T
Y
Chimpanzee
Pan troglodytes
XP_513978
271
31294
Y201
R
M
N
D
T
R
L
Y
H
E
A
D
K
T
Y
Rhesus Macaque
Macaca mulatta
XP_001091944
277
32074
K207
R
L
Y
H
E
I
S
K
S
Y
L
I
R
A
L
Dog
Lupus familis
XP_537207
473
52600
Y403
R
M
N
D
T
R
L
Y
H
E
A
D
K
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH58
271
31235
Y202
R
M
N
D
T
R
L
Y
H
E
A
D
K
T
Y
Rat
Rattus norvegicus
A2VCX1
271
31206
Y202
R
M
N
D
T
R
L
Y
H
E
A
D
K
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416593
274
31546
H201
R
M
N
D
T
R
L
H
H
E
S
D
K
A
Y
Frog
Xenopus laevis
Q6IRA8
259
29963
M196
V
D
G
V
L
I
R
M
N
D
T
R
L
Y
H
Zebra Danio
Brachydanio rerio
NP_956957
269
30986
Y205
R
I
N
D
T
R
L
Y
H
E
A
G
K
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608377
272
32319
D208
L
R
H
F
L
R
V
D
H
V
L
I
R
M
H
Honey Bee
Apis mellifera
XP_396151
311
35842
Y224
R
I
N
D
T
R
L
Y
H
E
F
G
Q
D
Y
Nematode Worm
Caenorhab. elegans
P34274
281
32890
T220
V
L
L
R
V
C
D
T
R
I
V
G
N
E
F
Sea Urchin
Strong. purpuratus
XP_791850
266
30474
T206
V
L
V
R
I
N
D
T
R
C
Y
H
E
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12199
356
41001
Y296
R
V
Y
D
T
R
I
Y
V
E
F
D
E
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.4
54.9
N.A.
96.6
95.9
N.A.
N.A.
79.9
76.4
66.9
N.A.
41.9
42.4
38.4
48.1
Protein Similarity:
100
99.6
95.3
56.6
N.A.
98.1
97.7
N.A.
N.A.
88.6
86.7
82.3
N.A.
61.7
64.3
56.9
68.3
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
80
0
73.3
N.A.
13.3
66.6
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
93.3
20
86.6
N.A.
40
80
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
43
0
0
22
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
65
0
0
15
8
0
8
0
50
0
8
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
65
0
0
15
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
15
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
22
0
0
8
% G
% His:
0
0
8
8
0
0
0
8
65
0
0
8
0
0
22
% H
% Ile:
0
15
0
0
8
15
8
0
0
8
0
15
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
50
8
0
% K
% Leu:
8
22
8
0
15
0
58
0
0
0
15
0
8
0
8
% L
% Met:
0
43
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
58
0
0
8
0
0
8
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
72
8
0
15
0
72
8
0
15
0
0
8
15
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
65
0
0
15
0
0
8
0
0
36
0
% T
% Val:
22
8
8
8
8
0
8
0
8
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
0
58
0
8
8
0
0
8
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _