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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIPRL
All Species:
41.52
Human Site:
Y116
Identified Species:
70.26
UniProt:
O75663
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75663
NP_001026970.1
272
31444
Y116
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Chimpanzee
Pan troglodytes
XP_513978
271
31294
Y115
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Rhesus Macaque
Macaca mulatta
XP_001091944
277
32074
Y116
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Dog
Lupus familis
XP_537207
473
52600
Y317
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH58
271
31235
Y116
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Rat
Rattus norvegicus
A2VCX1
271
31206
Y116
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416593
274
31546
Y115
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
D
Frog
Xenopus laevis
Q6IRA8
259
29963
Y116
D
W
T
Y
T
T
D
Y
K
G
T
L
L
G
D
Zebra Danio
Brachydanio rerio
NP_956957
269
30986
Y119
D
W
T
Y
T
T
D
Y
K
G
T
L
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608377
272
32319
Q138
W
T
F
T
S
T
Y
Q
G
T
M
N
E
K
V
Honey Bee
Apis mellifera
XP_396151
311
35842
T141
F
D
W
T
F
T
T
T
Y
T
G
T
I
S
N
Nematode Worm
Caenorhab. elegans
P34274
281
32890
T139
P
F
D
W
T
Y
T
T
H
Y
K
G
T
V
T
Sea Urchin
Strong. purpuratus
XP_791850
266
30474
Y123
D
W
T
Y
T
T
S
Y
K
G
T
I
V
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12199
356
41001
L197
N
D
V
N
D
D
S
L
N
I
I
H
K
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.4
54.9
N.A.
96.6
95.9
N.A.
N.A.
79.9
76.4
66.9
N.A.
41.9
42.4
38.4
48.1
Protein Similarity:
100
99.6
95.3
56.6
N.A.
98.1
97.7
N.A.
N.A.
88.6
86.7
82.3
N.A.
61.7
64.3
56.9
68.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
6.6
6.6
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
13.3
13.3
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
15
8
0
8
8
65
0
0
0
0
0
0
8
22
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
50
% E
% Phe:
8
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
72
8
8
0
65
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
8
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
72
0
8
0
8
8
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
65
58
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
8
0
0
8
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
15
0
0
0
0
0
0
8
8
% S
% Thr:
0
8
72
15
79
86
15
15
0
15
72
8
8
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
8
72
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
72
0
8
8
72
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _