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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIPRL
All Species:
20.3
Human Site:
S265
Identified Species:
34.36
UniProt:
O75663
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75663
NP_001026970.1
272
31444
S265
I
D
P
N
P
A
D
S
Q
K
S
T
Q
V
E
Chimpanzee
Pan troglodytes
XP_513978
271
31294
S264
I
D
P
N
P
A
D
S
Q
K
S
T
Q
V
E
Rhesus Macaque
Macaca mulatta
XP_001091944
277
32074
S270
I
D
P
N
P
A
D
S
Q
K
S
T
Q
V
E
Dog
Lupus familis
XP_537207
473
52600
S466
I
D
P
N
P
A
D
S
Q
E
S
R
P
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH58
271
31235
Rat
Rattus norvegicus
A2VCX1
271
31206
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416593
274
31546
S265
E
S
N
N
P
E
A
S
L
E
T
T
C
V
K
Frog
Xenopus laevis
Q6IRA8
259
29963
L252
I
Q
T
I
Y
E
K
L
E
F
P
S
Q
P
H
Zebra Danio
Brachydanio rerio
NP_956957
269
30986
A262
L
E
F
P
E
G
D
A
P
A
H
T
H
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608377
272
32319
S263
Q
E
F
V
P
V
K
S
K
Q
L
H
K
L
F
Honey Bee
Apis mellifera
XP_396151
311
35842
T300
V
T
D
N
T
A
T
T
T
N
I
N
D
I
N
Nematode Worm
Caenorhab. elegans
P34274
281
32890
S274
E
E
H
F
D
R
V
S
V
D
R
E
R
L
F
Sea Urchin
Strong. purpuratus
XP_791850
266
30474
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12199
356
41001
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.4
54.9
N.A.
96.6
95.9
N.A.
N.A.
79.9
76.4
66.9
N.A.
41.9
42.4
38.4
48.1
Protein Similarity:
100
99.6
95.3
56.6
N.A.
98.1
97.7
N.A.
N.A.
88.6
86.7
82.3
N.A.
61.7
64.3
56.9
68.3
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
N.A.
33.3
13.3
13.3
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
0
0
N.A.
N.A.
53.3
26.6
40
N.A.
46.6
33.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
36
8
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
29
8
0
8
0
36
0
0
8
0
0
8
0
0
% D
% Glu:
15
22
0
0
8
15
0
0
8
15
0
8
0
0
29
% E
% Phe:
0
0
15
8
0
0
0
0
0
8
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
8
8
0
8
% H
% Ile:
36
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
15
0
8
22
0
0
8
0
8
% K
% Leu:
8
0
0
0
0
0
0
8
8
0
8
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
43
0
0
0
0
0
8
0
8
0
0
8
% N
% Pro:
0
0
29
8
43
0
0
0
8
0
8
0
8
8
0
% P
% Gln:
8
8
0
0
0
0
0
0
29
8
0
0
29
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
8
8
0
0
% R
% Ser:
0
8
0
0
0
0
0
50
0
0
29
8
0
0
0
% S
% Thr:
0
8
8
0
8
0
8
8
8
0
8
36
0
8
0
% T
% Val:
8
0
0
8
0
8
8
0
8
0
0
0
0
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _