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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIPRL
All Species:
30.61
Human Site:
S216
Identified Species:
51.79
UniProt:
O75663
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75663
NP_001026970.1
272
31444
S216
Y
M
L
R
E
Y
T
S
R
E
S
K
I
S
S
Chimpanzee
Pan troglodytes
XP_513978
271
31294
S215
Y
M
L
R
E
Y
T
S
R
E
S
K
I
S
S
Rhesus Macaque
Macaca mulatta
XP_001091944
277
32074
N221
L
W
N
G
K
E
K
N
F
K
A
W
F
C
N
Dog
Lupus familis
XP_537207
473
52600
S417
Y
M
L
R
E
Y
T
S
R
E
S
K
I
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH58
271
31235
S216
Y
M
L
R
E
Y
T
S
R
E
S
K
I
A
N
Rat
Rattus norvegicus
A2VCX1
271
31206
S216
Y
M
L
R
E
Y
T
S
R
E
S
K
I
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416593
274
31546
S215
Y
M
L
R
E
Y
T
S
R
E
S
K
I
S
S
Frog
Xenopus laevis
Q6IRA8
259
29963
M210
H
E
A
D
K
T
F
M
L
R
E
Y
T
S
K
Zebra Danio
Brachydanio rerio
NP_956957
269
30986
T219
H
M
L
R
E
F
S
T
R
E
S
N
M
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608377
272
32319
E222
H
D
T
R
F
H
H
E
I
E
N
D
F
I
L
Honey Bee
Apis mellifera
XP_396151
311
35842
S238
Y
L
L
R
E
Y
T
S
R
E
A
K
I
E
E
Nematode Worm
Caenorhab. elegans
P34274
281
32890
E234
F
D
G
H
V
I
R
E
W
Q
L
R
E
A
K
Sea Urchin
Strong. purpuratus
XP_791850
266
30474
E220
G
T
N
Y
I
L
R
E
Y
S
S
K
E
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12199
356
41001
E310
V
V
I
R
E
S
K
E
F
E
G
K
Y
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.4
54.9
N.A.
96.6
95.9
N.A.
N.A.
79.9
76.4
66.9
N.A.
41.9
42.4
38.4
48.1
Protein Similarity:
100
99.6
95.3
56.6
N.A.
98.1
97.7
N.A.
N.A.
88.6
86.7
82.3
N.A.
61.7
64.3
56.9
68.3
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
N.A.
100
6.6
46.6
N.A.
13.3
73.3
0
20
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
N.A.
100
20
86.6
N.A.
33.3
86.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
15
0
0
36
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
0
8
0
0
0
0
0
0
0
8
0
0
15
% D
% Glu:
0
8
0
0
65
8
0
29
0
72
8
0
15
8
8
% E
% Phe:
8
0
0
0
8
8
8
0
15
0
0
0
15
0
0
% F
% Gly:
8
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
22
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
8
0
0
0
50
8
0
% I
% Lys:
0
0
0
0
15
0
15
0
0
8
0
65
0
8
15
% K
% Leu:
8
8
58
0
0
8
0
0
8
0
8
0
0
0
8
% L
% Met:
0
50
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
0
0
0
0
8
0
0
8
8
0
0
29
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
72
0
0
15
0
58
8
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
50
0
8
58
0
0
29
29
% S
% Thr:
0
8
8
0
0
8
50
8
0
0
0
0
8
0
0
% T
% Val:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
50
0
0
8
0
50
0
0
8
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _