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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKRA All Species: 21.82
Human Site: T214 Identified Species: 48
UniProt: O75569 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75569 NP_001132989.1 313 34404 T214 V G H S L G C T W H S L R N S
Chimpanzee Pan troglodytes XP_001156031 270 29651 W172 G H S L G C T W H S L R N S P
Rhesus Macaque Macaca mulatta XP_001098583 302 33088 W204 G H S L G C T W H S L R N S P
Dog Lupus familis XP_545545 313 34342 T214 V G H S L G C T W H S L R N S
Cat Felis silvestris
Mouse Mus musculus Q9WTX2 313 34353 T214 V G H S L G C T W H S L R N S
Rat Rattus norvegicus Q4V8C7 313 34337 T214 V G H S L G C T W H S L R N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515387 397 42380 T298 I G N N L G C T W D A M K N S
Chicken Gallus gallus
Frog Xenopus laevis Q7ZYA5 309 34051 T210 I G N K M G C T W D S M R N S
Zebra Danio Brachydanio rerio B0V3F8 282 30822 V184 S P P S R V Y V E S L R N S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624606 338 37626 Q240 H A A H K M W Q A L H Y M T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797998 306 33757 F208 L K M N P L N F P D P T Y S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 95.2 99.3 N.A. 98 97.7 N.A. 51.3 N.A. 61.3 47.9 N.A. N.A. 22.4 N.A. 35.4
Protein Similarity: 100 86.2 95.2 99.6 N.A. 99.3 99.3 N.A. 64.4 N.A. 75.4 63.2 N.A. N.A. 40.2 N.A. 49.8
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 53.3 N.A. 60 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 6.6 6.6 100 N.A. 100 100 N.A. 93.3 N.A. 86.6 20 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 19 55 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 19 55 0 0 19 55 0 0 0 0 0 0 0 0 0 % G
% His: 10 19 37 10 0 0 0 0 19 37 10 0 0 0 0 % H
% Ile: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 10 10 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 0 19 46 10 0 0 0 10 28 37 0 0 0 % L
% Met: 0 0 10 0 10 10 0 0 0 0 0 19 10 0 0 % M
% Asn: 0 0 19 19 0 0 10 0 0 0 0 0 28 55 0 % N
% Pro: 0 10 10 0 10 0 0 0 10 0 10 0 0 0 19 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 28 46 0 0 % R
% Ser: 10 0 19 46 0 0 0 0 0 28 46 0 0 37 64 % S
% Thr: 0 0 0 0 0 0 19 55 0 0 0 10 0 10 19 % T
% Val: 37 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 19 55 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _