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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKRA
All Species:
13.33
Human Site:
S246
Identified Species:
29.33
UniProt:
O75569
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75569
NP_001132989.1
313
34404
S246
T
D
Y
I
Q
L
L
S
E
I
A
K
E
Q
G
Chimpanzee
Pan troglodytes
XP_001156031
270
29651
E204
D
Y
I
Q
L
L
S
E
I
A
K
E
Q
G
F
Rhesus Macaque
Macaca mulatta
XP_001098583
302
33088
E236
D
Y
I
Q
L
L
S
E
I
A
K
E
Q
G
F
Dog
Lupus familis
XP_545545
313
34342
S246
T
D
Y
I
Q
L
L
S
E
I
A
K
E
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX2
313
34353
S246
T
D
Y
I
Q
L
L
S
E
I
A
S
E
Q
G
Rat
Rattus norvegicus
Q4V8C7
313
34337
S246
T
D
Y
I
Q
L
L
S
E
I
A
K
E
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515387
397
42380
G330
T
D
Y
I
Q
L
L
G
E
V
A
E
E
Q
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYA5
309
34051
K242
T
D
Y
V
K
M
L
K
D
V
A
E
E
L
D
Zebra Danio
Brachydanio rerio
B0V3F8
282
30822
E216
D
Y
I
Q
M
L
L
E
I
S
L
E
L
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624606
338
37626
Q272
V
N
L
V
Q
F
L
Q
E
I
A
S
E
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797998
306
33757
G240
I
E
E
Q
T
Q
A
G
H
Y
Q
C
F
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
95.2
99.3
N.A.
98
97.7
N.A.
51.3
N.A.
61.3
47.9
N.A.
N.A.
22.4
N.A.
35.4
Protein Similarity:
100
86.2
95.2
99.6
N.A.
99.3
99.3
N.A.
64.4
N.A.
75.4
63.2
N.A.
N.A.
40.2
N.A.
49.8
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
100
N.A.
80
N.A.
40
13.3
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
100
20
20
100
N.A.
93.3
100
N.A.
93.3
N.A.
80
20
N.A.
N.A.
60
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
19
64
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
28
55
0
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
10
10
0
0
0
0
28
55
0
0
46
64
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
28
% F
% Gly:
0
0
0
0
0
0
0
19
0
0
0
0
0
28
46
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
28
46
0
0
0
0
28
46
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
19
28
0
0
0
% K
% Leu:
0
0
10
0
19
73
73
0
0
0
10
0
10
10
0
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
37
55
10
0
10
0
0
10
0
19
55
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
19
37
0
10
0
19
0
0
0
% S
% Thr:
55
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
19
0
0
0
0
0
19
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
28
55
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _