KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EED
All Species:
23.03
Human Site:
S34
Identified Species:
42.22
UniProt:
O75530
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75530
NP_003788.2
441
50198
S34
E
N
S
N
P
D
L
S
G
D
E
N
D
D
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102402
466
53042
S34
E
N
S
N
P
D
L
S
G
D
E
N
D
D
A
Dog
Lupus familis
XP_533985
466
53042
S34
E
N
S
N
P
D
L
S
G
D
E
N
D
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q921E6
441
50179
S34
E
N
S
N
P
D
L
S
G
D
E
N
D
D
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511506
448
50852
D41
V
G
Q
A
A
S
G
D
E
V
A
R
D
D
A
Chicken
Gallus gallus
Q5ZKH3
446
50359
S39
N
S
N
P
G
D
L
S
G
D
E
N
D
D
A
Frog
Xenopus laevis
Q8UUP2
438
49707
E34
N
P
E
L
S
G
D
E
N
D
D
S
V
S
I
Zebra Danio
Brachydanio rerio
Q566T0
443
50598
S36
E
N
S
N
P
D
L
S
G
D
D
N
D
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24338
425
47969
R34
T
T
N
S
T
T
S
R
S
K
S
P
S
S
S
Honey Bee
Apis mellifera
XP_623808
427
48821
T34
C
S
I
G
S
N
S
T
A
G
T
H
R
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786345
461
51844
E54
D
I
D
D
S
K
S
E
T
T
S
Q
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8VZY6
379
42484
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT47
369
41239
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
94.6
N.A.
100
N.A.
N.A.
90.8
95.9
93.1
89.6
N.A.
49.8
56.2
N.A.
58.1
Protein Similarity:
100
N.A.
94.6
94.6
N.A.
100
N.A.
N.A.
92.4
97
96.1
95.2
N.A.
68.2
72.5
N.A.
73.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
20
66.6
6.6
93.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
20
80
20
100
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
36.5
N.A.
34.6
N.A.
N.A.
Protein Similarity:
N.A.
54.4
N.A.
53
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
8
0
8
0
0
0
54
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
47
8
8
0
54
16
0
54
54
16
% D
% Glu:
39
0
8
0
0
0
0
16
8
0
39
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
8
8
0
47
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
47
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
39
16
39
0
8
0
0
8
0
0
47
0
0
0
% N
% Pro:
0
8
0
8
39
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
0
16
39
8
24
8
24
47
8
0
16
8
16
24
8
% S
% Thr:
8
8
0
0
8
8
0
8
8
8
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _