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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSIP1 All Species: 20
Human Site: S500 Identified Species: 48.89
UniProt: O75475 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75475 NP_001121689.1 530 60103 S500 N G E S N E D S K D N H E A S
Chimpanzee Pan troglodytes XP_520495 821 89410 S791 N G E S N E D S K D N H E A S
Rhesus Macaque Macaca mulatta XP_001110685 530 60163 S500 N G E S N E E S K D N H E A S
Dog Lupus familis XP_531939 530 60220 S500 N G D S S E E S K D N H E A S
Cat Felis silvestris
Mouse Mus musculus Q99JF8 528 59678 G498 N G D S N E D G K D S R E A S
Rat Rattus norvegicus Q812D1 528 59620 S498 N G D S A E E S K D S R E A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507936 388 43989 E359 D E S K D K H E V S P N K K T
Chicken Gallus gallus Q5XXA9 579 64909 K549 N G E N A E E K D K L E V A S
Frog Xenopus laevis Q32N87 642 72361 T613 D N K A E M E T K Q N N H A E
Zebra Danio Brachydanio rerio Q5XXA7 662 73469 A630 R P D P D E P A D Q L N D S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64 93.4 97.3 N.A. 92.2 91.5 N.A. 50.3 69.9 35 32.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 64.4 95.4 99 N.A. 96 95.2 N.A. 58.8 78.7 53.4 52.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 73.3 60 N.A. 0 40 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 80 N.A. 40 53.3 60 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 20 0 0 10 0 0 0 0 0 80 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 40 0 20 0 30 0 20 60 0 0 10 0 0 % D
% Glu: 0 10 40 0 10 80 50 10 0 0 0 10 60 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 70 0 0 0 0 0 10 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 40 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 0 10 0 10 70 10 0 0 10 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 70 10 0 10 40 0 0 0 0 0 50 30 0 0 0 % N
% Pro: 0 10 0 10 0 0 10 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % R
% Ser: 0 0 10 60 10 0 0 50 0 10 20 0 0 10 60 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 20 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _