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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNA1 All Species: 31.21
Human Site: S99 Identified Species: 49.05
UniProt: O75449 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75449 NP_008975.1 491 55965 S99 A S E G E V W S M P V P V E R
Chimpanzee Pan troglodytes XP_001173237 491 55916 S99 A S E G E V W S M P V P V E R
Rhesus Macaque Macaca mulatta XP_001086813 396 44879 K63 A V R C R E K K E Q N K G R E
Dog Lupus familis XP_533445 491 55924 S99 A S E G E V W S L P V P V E R
Cat Felis silvestris
Mouse Mus musculus Q9WV86 491 55931 S99 A A E G E V W S L P V P V E R
Rat Rattus norvegicus Q6E0V2 491 55825 S99 S S E G E V W S L P V P V E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506598 493 55773 S99 T P D G E V W S L P V P V E R
Chicken Gallus gallus Q1HGK7 492 56020 S99 A H D A E V W S L P V P A E R
Frog Xenopus laevis Q9PUL2 486 55412 S99 S H D G E V W S L P V P V E R
Zebra Danio Brachydanio rerio Q5RII9 485 54863 I94 S F A Q D N D I M P V H V E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397402 506 57695 N109 P T L W T Y N N S D N S W N Q
Nematode Worm Caenorhab. elegans P34808 472 51721 P95 R Q S G S P E P P A D P D V W
Sea Urchin Strong. purpuratus O61577 516 57575 H99 A P F S H H Q H A A K P A A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 T132 R P P T R D V T S R R P A R A
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 S90 K K S P S A G S G S N G G N K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.6 97.3 N.A. 93 93.4 N.A. 91 88.6 84.5 77.1 N.A. N.A. 56.5 34.4 60.6
Protein Similarity: 100 99.8 79.8 98.7 N.A. 95.9 96.7 N.A. 94.9 94.5 91 85.7 N.A. N.A. 71.9 53.3 74
P-Site Identity: 100 100 6.6 93.3 N.A. 86.6 86.6 N.A. 73.3 66.6 73.3 33.3 N.A. N.A. 0 13.3 13.3
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 86.6 80 93.3 46.6 N.A. N.A. 20 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 49.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 7 7 7 0 7 0 0 7 14 0 0 20 7 14 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 7 7 7 0 0 7 7 0 7 0 0 % D
% Glu: 0 0 34 0 54 7 7 0 7 0 0 0 0 60 7 % E
% Phe: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 54 0 0 7 0 7 0 0 7 14 0 0 % G
% His: 0 14 0 0 7 7 0 7 0 0 0 7 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 7 0 0 0 0 7 7 0 0 7 7 0 0 7 % K
% Leu: 0 0 7 0 0 0 0 0 40 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 7 7 0 0 20 0 0 14 0 % N
% Pro: 7 20 7 7 0 7 0 7 7 60 0 74 0 0 0 % P
% Gln: 0 7 0 7 0 0 7 0 0 7 0 0 0 0 7 % Q
% Arg: 14 0 7 0 14 0 0 0 0 7 7 0 0 14 54 % R
% Ser: 20 27 14 7 14 0 0 60 14 7 0 7 0 0 0 % S
% Thr: 7 7 0 7 7 0 0 7 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 0 54 7 0 0 0 60 0 54 7 0 % V
% Trp: 0 0 0 7 0 0 54 0 0 0 0 0 7 0 7 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _