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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KATNA1
All Species:
30.3
Human Site:
S449
Identified Species:
47.62
UniProt:
O75449
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75449
NP_008975.1
491
55965
S449
P
E
E
I
R
N
L
S
K
E
E
M
H
M
P
Chimpanzee
Pan troglodytes
XP_001173237
491
55916
S449
P
E
E
I
R
N
L
S
K
E
E
M
H
M
P
Rhesus Macaque
Macaca mulatta
XP_001086813
396
44879
K355
E
E
I
R
N
L
S
K
E
E
M
H
M
P
T
Dog
Lupus familis
XP_533445
491
55924
S449
P
E
E
I
R
N
L
S
R
E
E
M
H
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV86
491
55931
S449
P
E
E
I
R
N
L
S
R
E
A
M
H
M
P
Rat
Rattus norvegicus
Q6E0V2
491
55825
S449
P
E
E
I
R
N
L
S
R
E
E
M
H
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506598
493
55773
S451
P
E
E
I
R
N
L
S
R
D
E
M
H
M
P
Chicken
Gallus gallus
Q1HGK7
492
56020
S450
P
E
E
I
R
N
L
S
R
D
E
M
H
M
P
Frog
Xenopus laevis
Q9PUL2
486
55412
N444
L
T
P
E
E
I
R
N
L
S
R
D
D
M
H
Zebra Danio
Brachydanio rerio
Q5RII9
485
54863
P443
P
E
E
I
R
N
L
P
K
D
E
M
H
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397402
506
57695
P464
P
D
Q
I
R
Q
L
P
K
E
E
L
D
L
P
Nematode Worm
Caenorhab. elegans
P34808
472
51721
A429
R
G
G
E
L
T
A
A
M
E
S
L
K
A
E
Sea Urchin
Strong. purpuratus
O61577
516
57575
P474
P
E
E
I
R
H
I
P
K
E
E
L
N
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S480
R
D
E
I
K
N
M
S
K
D
D
I
S
N
D
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
A393
M
S
W
T
D
I
E
A
D
E
L
K
E
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.6
97.3
N.A.
93
93.4
N.A.
91
88.6
84.5
77.1
N.A.
N.A.
56.5
34.4
60.6
Protein Similarity:
100
99.8
79.8
98.7
N.A.
95.9
96.7
N.A.
94.9
94.5
91
85.7
N.A.
N.A.
71.9
53.3
74
P-Site Identity:
100
100
13.3
93.3
N.A.
86.6
93.3
N.A.
86.6
86.6
6.6
86.6
N.A.
N.A.
53.3
6.6
60
P-Site Similarity:
100
100
20
100
N.A.
93.3
100
N.A.
100
100
13.3
93.3
N.A.
N.A.
80
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
35.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.7
54.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
14
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
0
7
0
0
0
7
27
7
7
14
0
14
% D
% Glu:
7
67
67
14
7
0
7
0
7
67
60
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
7
54
0
7
% H
% Ile:
0
0
7
74
0
14
7
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
7
40
0
0
7
7
0
0
% K
% Leu:
7
0
0
0
7
7
60
0
7
0
7
20
0
7
0
% L
% Met:
7
0
0
0
0
0
7
0
7
0
7
54
7
60
0
% M
% Asn:
0
0
0
0
7
60
0
7
0
0
0
0
7
7
0
% N
% Pro:
67
0
7
0
0
0
0
20
0
0
0
0
0
14
67
% P
% Gln:
0
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% Q
% Arg:
14
0
0
7
67
0
7
0
34
0
7
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
7
54
0
7
7
0
7
0
0
% S
% Thr:
0
7
0
7
0
7
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _