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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNA1 All Species: 13.33
Human Site: S125 Identified Species: 20.95
UniProt: O75449 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75449 NP_008975.1 491 55965 S125 S Q Y S D P K S H G N R P S T
Chimpanzee Pan troglodytes XP_001173237 491 55916 S125 S Q Y S D P K S H G N R P S T
Rhesus Macaque Macaca mulatta XP_001086813 396 44879 S89 P E T N K F D S T G Y D K D L
Dog Lupus familis XP_533445 491 55924 P125 P Q Y S D P K P H G N R P G T
Cat Felis silvestris
Mouse Mus musculus Q9WV86 491 55931 P125 S Q H S D P K P H S N R P S T
Rat Rattus norvegicus Q6E0V2 491 55825 P125 T Q H S D P K P H S N R P G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506598 493 55773 T125 A Q C S D S R T H S N R P G V
Chicken Gallus gallus Q1HGK7 492 56020 G125 A Q Y S D C R G H N N R I S A
Frog Xenopus laevis Q9PUL2 486 55412 S125 V Q C N D N K S H N N R F S A
Zebra Danio Brachydanio rerio Q5RII9 485 54863 G120 V P Y K D S K G H G N R L S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397402 506 57695 N135 L T P A E Q K N I K P L K N Q
Nematode Worm Caenorhab. elegans P34808 472 51721 G121 K F G A T K K G V G A A G P R
Sea Urchin Strong. purpuratus O61577 516 57575 P125 P T P V D H R P S P P Y Q R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 T158 G A W A R G P T T R T G P A S
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 R116 G E D N K K L R G A L S S A I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.6 97.3 N.A. 93 93.4 N.A. 91 88.6 84.5 77.1 N.A. N.A. 56.5 34.4 60.6
Protein Similarity: 100 99.8 79.8 98.7 N.A. 95.9 96.7 N.A. 94.9 94.5 91 85.7 N.A. N.A. 71.9 53.3 74
P-Site Identity: 100 100 13.3 80 N.A. 80 60 N.A. 46.6 53.3 53.3 53.3 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 100 100 26.6 80 N.A. 86.6 73.3 N.A. 66.6 66.6 60 53.3 N.A. N.A. 33.3 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 49.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 20 0 0 0 0 0 7 7 7 0 14 27 % A
% Cys: 0 0 14 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 67 0 7 0 0 0 0 7 0 7 0 % D
% Glu: 0 14 0 0 7 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 7 0 0 0 0 0 0 7 0 0 % F
% Gly: 14 0 7 0 0 7 0 20 7 40 0 7 7 20 0 % G
% His: 0 0 14 0 0 7 0 0 60 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 7 % I
% Lys: 7 0 0 7 14 14 60 0 0 7 0 0 14 0 0 % K
% Leu: 7 0 0 0 0 0 7 0 0 0 7 7 7 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 7 0 7 0 14 60 0 0 7 0 % N
% Pro: 20 7 14 0 0 34 7 27 0 7 14 0 47 7 0 % P
% Gln: 0 54 0 0 0 7 0 0 0 0 0 0 7 0 7 % Q
% Arg: 0 0 0 0 7 0 20 7 0 7 0 60 0 7 7 % R
% Ser: 20 0 0 47 0 14 0 27 7 20 0 7 7 40 7 % S
% Thr: 7 14 7 0 7 0 0 14 14 0 7 0 0 0 27 % T
% Val: 14 0 0 7 0 0 0 0 7 0 0 0 0 0 14 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 34 0 0 0 0 0 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _