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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40A
All Species:
23.03
Human Site:
T478
Identified Species:
42.22
UniProt:
O75400
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75400
NP_060362.3
957
108805
T478
L
E
N
H
E
K
M
T
S
T
T
R
Y
K
K
Chimpanzee
Pan troglodytes
XP_515837
972
110432
T493
L
E
N
H
E
K
M
T
S
T
T
R
Y
K
K
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
L433
Y
D
D
V
L
F
F
L
A
K
K
E
K
E
Q
Dog
Lupus familis
XP_533359
874
99942
S433
E
D
V
L
F
F
L
S
K
K
E
K
E
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C7
953
108462
T474
L
E
N
H
E
K
M
T
S
T
T
R
Y
K
K
Rat
Rattus norvegicus
NP_001099950
953
108455
T474
L
E
N
H
E
K
M
T
S
T
T
R
Y
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
E443
E
V
W
N
A
I
S
E
R
D
R
L
E
I
Y
Chicken
Gallus gallus
NP_989492
853
96992
Y448
E
R
D
R
L
E
I
Y
E
D
V
L
F
F
L
Frog
Xenopus laevis
NP_001121292
487
54707
L90
A
T
H
V
S
Q
G
L
P
P
S
M
Q
A
A
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
T439
L
D
N
M
A
N
V
T
Y
R
T
T
W
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
M408
N
D
V
T
L
L
G
M
D
K
E
D
A
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
K327
K
A
S
D
I
F
S
K
E
P
L
W
I
A
V
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
T757
L
Q
H
H
P
K
M
T
S
T
T
R
Y
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
51.8
89.6
N.A.
96
96.2
N.A.
74.4
70.9
30.2
66
N.A.
41.1
N.A.
30.5
35.3
Protein Similarity:
100
98
65.6
90.6
N.A.
97.5
97.3
N.A.
78.4
75.4
36.5
74.6
N.A.
57.2
N.A.
50.2
46.5
P-Site Identity:
100
100
0
0
N.A.
100
100
N.A.
0
0
0
26.6
N.A.
0
N.A.
0
73.3
P-Site Similarity:
100
100
33.3
33.3
N.A.
100
100
N.A.
6.6
26.6
20
53.3
N.A.
6.6
N.A.
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
16
0
0
0
8
0
0
0
8
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
16
8
0
0
0
0
8
16
0
8
0
0
0
% D
% Glu:
24
31
0
0
31
8
0
8
16
0
16
8
16
8
8
% E
% Phe:
0
0
0
0
8
24
8
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
39
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
8
0
0
0
0
0
8
8
8
% I
% Lys:
8
0
0
0
0
39
0
8
8
24
8
8
8
31
39
% K
% Leu:
47
0
0
8
24
8
8
16
0
0
8
16
0
8
8
% L
% Met:
0
0
0
8
0
0
39
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
39
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
16
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
8
% Q
% Arg:
0
8
0
8
0
0
0
0
8
8
8
39
0
8
0
% R
% Ser:
0
0
8
0
8
0
16
8
39
0
8
0
0
8
0
% S
% Thr:
0
8
0
8
0
0
0
47
0
39
47
8
0
0
0
% T
% Val:
0
8
16
16
0
0
8
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
8
0
0
0
39
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _