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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40A
All Species:
19.09
Human Site:
S815
Identified Species:
35
UniProt:
O75400
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75400
NP_060362.3
957
108805
S815
H
S
K
N
K
K
H
S
K
K
S
K
K
H
H
Chimpanzee
Pan troglodytes
XP_515837
972
110432
S830
H
Q
K
N
R
T
F
S
K
K
S
K
K
H
H
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
E721
F
L
Q
V
L
E
T
E
C
Q
H
L
H
T
K
Dog
Lupus familis
XP_533359
874
99942
S732
H
S
K
N
K
K
H
S
K
K
S
K
K
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C7
953
108462
S811
H
S
K
N
K
K
H
S
K
K
S
K
K
H
H
Rat
Rattus norvegicus
NP_001099950
953
108455
S811
H
S
K
N
K
K
H
S
K
K
S
K
K
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
R713
D
A
V
W
E
D
I
R
E
R
F
V
K
E
P
Chicken
Gallus gallus
NP_989492
853
96992
R713
V
W
E
D
I
R
D
R
F
V
K
E
P
A
F
Frog
Xenopus laevis
NP_001121292
487
54707
P347
L
L
K
E
K
R
V
P
S
N
A
T
W
E
Q
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
K710
S
K
T
K
K
H
S
K
K
S
K
K
H
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
I666
R
S
V
S
R
S
D
I
E
N
E
H
I
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
E584
R
K
R
R
L
E
S
E
F
R
N
L
L
K
E
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
S1092
H
H
H
G
K
S
T
S
R
K
H
S
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
51.8
89.6
N.A.
96
96.2
N.A.
74.4
70.9
30.2
66
N.A.
41.1
N.A.
30.5
35.3
Protein Similarity:
100
98
65.6
90.6
N.A.
97.5
97.3
N.A.
78.4
75.4
36.5
74.6
N.A.
57.2
N.A.
50.2
46.5
P-Site Identity:
100
73.3
0
100
N.A.
100
100
N.A.
6.6
0
13.3
26.6
N.A.
6.6
N.A.
0
33.3
P-Site Similarity:
100
80
20
100
N.A.
100
100
N.A.
33.3
26.6
26.6
26.6
N.A.
26.6
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
8
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
8
16
0
16
16
0
8
8
0
24
8
% E
% Phe:
8
0
0
0
0
0
8
0
16
0
8
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
47
8
8
0
0
8
31
0
0
0
16
8
16
47
39
% H
% Ile:
0
0
0
0
8
0
8
8
0
0
0
0
8
0
0
% I
% Lys:
0
16
47
8
54
31
0
8
47
47
16
47
54
16
8
% K
% Leu:
8
16
0
0
16
0
0
0
0
0
0
16
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
39
0
0
0
0
0
16
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% P
% Gln:
0
8
8
0
0
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
16
0
8
8
16
16
0
16
8
16
0
0
0
0
8
% R
% Ser:
8
39
0
8
0
16
16
47
8
8
39
8
0
0
8
% S
% Thr:
0
0
8
0
0
8
16
0
0
0
0
8
0
8
0
% T
% Val:
8
0
16
8
0
0
8
0
0
8
0
8
0
0
8
% V
% Trp:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _