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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TULP3 All Species: 4.55
Human Site: Y224 Identified Species: 7.69
UniProt: O75386 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75386 NP_003315.2 442 49642 Y224 L F P T Y Y M Y L E K E E N Q
Chimpanzee Pan troglodytes XP_508932 270 30236 P62 A R L R R A K P R A S D E Q T
Rhesus Macaque Macaca mulatta XP_001098680 454 51179 Y223 L F P T Y Y M Y L E K E E N Q
Dog Lupus familis XP_854644 442 49697 H224 L F P T Y Y M H L E K D E N R
Cat Felis silvestris
Mouse Mus musculus O88413 460 51212 H242 L F P T Y Y M H L E R E E N R
Rat Rattus norvegicus O88808 505 55299 H286 M Y P T Y F L H L D R E D G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508810 461 50869 H243 L F P T Y Y M H L E R E D N R
Chicken Gallus gallus XP_423762 466 52562 H247 L F P T Y Y M H L E K D N N R
Frog Xenopus laevis NP_001086614 506 56802 H288 L Y P T Y Y M H L E R D D T R
Zebra Danio Brachydanio rerio XP_697114 530 58796 H312 M Y P T Y Y L H L E R E D G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395938 415 47214 H197 L Y P T Y F L H L E R D Y G K
Nematode Worm Caenorhab. elegans Q09306 426 48435 H203 M F P T Y F L H L E E F D T D
Sea Urchin Strong. purpuratus XP_786268 403 44135 R188 T Y Y L H M E R D D G R K Q F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VY21 406 45293 F192 I G K L R S N F L G T K F T V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.6 92.5 74.8 N.A. 68.6 51 N.A. 64.2 62.6 54.9 50.3 N.A. N.A. 46.1 39.8 44.8
Protein Similarity: 100 60.8 94.2 83.9 N.A. 80.4 65.5 N.A. 76.1 76.1 68.5 62.8 N.A. N.A. 64 59.9 61.5
P-Site Identity: 100 6.6 100 80 N.A. 80 33.3 N.A. 73.3 73.3 53.3 46.6 N.A. N.A. 40 40 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 93.3 N.A. N.A. 86.6 80 26.6
Percent
Protein Identity: N.A. N.A. N.A. 22.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 15 0 36 36 0 8 % D
% Glu: 0 0 0 0 0 0 8 0 0 72 8 43 36 0 0 % E
% Phe: 0 50 0 0 0 22 0 8 0 0 0 8 8 0 8 % F
% Gly: 0 8 0 0 0 0 0 0 0 8 8 0 0 22 0 % G
% His: 0 0 0 0 8 0 0 65 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 8 0 0 0 29 8 8 0 22 % K
% Leu: 58 0 8 15 0 0 29 0 86 0 0 0 0 0 0 % L
% Met: 22 0 0 0 0 8 50 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 8 43 0 % N
% Pro: 0 0 79 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 15 % Q
% Arg: 0 8 0 8 15 0 0 8 8 0 43 8 0 0 36 % R
% Ser: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % S
% Thr: 8 0 0 79 0 0 0 0 0 0 8 0 0 22 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 36 8 0 79 58 0 15 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _