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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TULP3
All Species:
45.15
Human Site:
Y221
Identified Species:
76.41
UniProt:
O75386
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75386
NP_003315.2
442
49642
Y221
D
R
G
L
F
P
T
Y
Y
M
Y
L
E
K
E
Chimpanzee
Pan troglodytes
XP_508932
270
30236
R59
N
P
E
A
R
L
R
R
A
K
P
R
A
S
D
Rhesus Macaque
Macaca mulatta
XP_001098680
454
51179
Y220
D
R
G
L
F
P
T
Y
Y
M
Y
L
E
K
E
Dog
Lupus familis
XP_854644
442
49697
Y221
D
R
G
L
F
P
T
Y
Y
M
H
L
E
K
D
Cat
Felis silvestris
Mouse
Mus musculus
O88413
460
51212
Y239
D
R
G
L
F
P
T
Y
Y
M
H
L
E
R
E
Rat
Rattus norvegicus
O88808
505
55299
Y283
D
R
G
M
Y
P
T
Y
F
L
H
L
D
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508810
461
50869
Y240
D
R
G
L
F
P
T
Y
Y
M
H
L
E
R
E
Chicken
Gallus gallus
XP_423762
466
52562
Y244
D
R
G
L
F
P
T
Y
Y
M
H
L
E
K
D
Frog
Xenopus laevis
NP_001086614
506
56802
Y285
D
R
G
L
Y
P
T
Y
Y
M
H
L
E
R
D
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
Y309
D
R
G
M
Y
P
T
Y
Y
L
H
L
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395938
415
47214
Y194
D
R
G
L
Y
P
T
Y
F
L
H
L
E
R
D
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
Y200
D
K
G
M
F
P
T
Y
F
L
H
L
E
E
F
Sea Urchin
Strong. purpuratus
XP_786268
403
44135
H185
V
Y
P
T
Y
Y
L
H
M
E
R
D
D
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
R189
N
T
Y
I
G
K
L
R
S
N
F
L
G
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
92.5
74.8
N.A.
68.6
51
N.A.
64.2
62.6
54.9
50.3
N.A.
N.A.
46.1
39.8
44.8
Protein Similarity:
100
60.8
94.2
83.9
N.A.
80.4
65.5
N.A.
76.1
76.1
68.5
62.8
N.A.
N.A.
64
59.9
61.5
P-Site Identity:
100
0
100
86.6
N.A.
86.6
53.3
N.A.
86.6
86.6
73.3
66.6
N.A.
N.A.
60
53.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
100
93.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
79
0
0
0
0
0
0
0
0
0
0
8
15
0
36
% D
% Glu:
0
0
8
0
0
0
0
0
0
8
0
0
72
8
43
% E
% Phe:
0
0
0
0
50
0
0
0
22
0
8
0
0
0
8
% F
% Gly:
0
0
79
0
8
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
65
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
8
0
0
0
29
8
% K
% Leu:
0
0
0
58
0
8
15
0
0
29
0
86
0
0
0
% L
% Met:
0
0
0
22
0
0
0
0
8
50
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
79
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
72
0
0
8
0
8
15
0
0
8
8
0
43
8
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% S
% Thr:
0
8
0
8
0
0
79
0
0
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
36
8
0
79
58
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _