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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAMP4
All Species:
15.45
Human Site:
Y139
Identified Species:
24.29
UniProt:
O75379
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75379
NP_003753.2
141
16397
Y139
I
I
L
I
V
M
K
Y
R
T
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_514347
124
14309
V121
I
I
I
I
I
V
W
V
V
S
S
_
_
_
_
Rhesus Macaque
Macaca mulatta
Q9N0Y0
116
12644
F114
L
I
I
I
I
V
Y
F
S
T
_
_
_
_
_
Dog
Lupus familis
XP_537195
141
16319
Y139
I
I
L
T
V
L
K
Y
R
A
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O70480
141
16334
F139
I
I
L
I
V
V
K
F
R
T
_
_
_
_
_
Rat
Rattus norvegicus
P63025
103
11462
W100
I
V
I
I
I
I
V
W
C
V
S
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515123
141
16444
Y139
I
I
P
L
V
L
K
Y
R
T
_
_
_
_
_
Chicken
Gallus gallus
XP_001233852
159
18204
Y157
I
I
P
I
V
L
K
Y
H
T
_
_
_
_
_
Frog
Xenopus laevis
P47193
114
12454
F112
L
I
I
I
I
V
Y
F
S
T
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_957029
68
7914
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18489
152
16693
W131
I
I
V
L
V
S
V
W
P
S
S
S
D
S
G
Honey Bee
Apis mellifera
XP_394684
145
16557
Y141
V
L
D
I
M
V
L
Y
L
V
L
R
_
_
_
Nematode Worm
Caenorhab. elegans
O02495
109
12007
W105
L
I
I
I
I
V
L
W
A
G
G
K
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFP1
221
25302
Y204
L
V
L
A
L
V
V
Y
I
A
M
A
F
V
C
Baker's Yeast
Sacchar. cerevisiae
P33328
115
12939
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
29
96.4
N.A.
97.1
29.7
N.A.
91.4
79.8
29.7
41.1
N.A.
22.3
31
27.6
N.A.
Protein Similarity:
100
56
49.6
97.8
N.A.
99.2
52.4
N.A.
97.8
85.5
48.2
46.8
N.A.
50
56.5
49.6
N.A.
P-Site Identity:
100
27.2
30
70
N.A.
80
18.1
N.A.
70
70
30
0
N.A.
20
16.6
16.6
N.A.
P-Site Similarity:
100
63.6
80
80
N.A.
100
63.6
N.A.
90
80
80
0
N.A.
53.3
50
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
28.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
14
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
54
67
34
60
34
7
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
0
0
7
0
0
0
% K
% Leu:
27
7
27
14
7
20
14
0
7
0
7
0
0
0
0
% L
% Met:
0
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
14
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
27
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
14
14
20
7
0
7
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
40
0
0
0
0
0
% T
% Val:
7
14
7
0
40
47
20
7
7
14
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
7
20
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
47
60
74
74
74
% _