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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTP4A3
All Species:
40.3
Human Site:
T22
Identified Species:
88.67
UniProt:
O75365
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75365
NP_009010.2
173
19535
T22
K
H
M
R
F
L
I
T
H
N
P
T
N
A
T
Chimpanzee
Pan troglodytes
XP_001148475
173
19530
T22
K
H
M
R
F
L
I
T
H
N
P
T
N
A
T
Rhesus Macaque
Macaca mulatta
XP_001083424
173
19607
T22
K
N
I
R
F
L
I
T
H
N
P
T
N
V
T
Dog
Lupus familis
XP_848534
173
19436
T22
K
S
M
R
F
L
I
T
H
N
P
T
N
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D658
173
19633
T22
R
H
M
R
F
L
I
T
H
N
P
S
N
A
T
Rat
Rattus norvegicus
Q78EG7
173
19797
T22
K
N
M
R
F
L
I
T
H
N
P
T
N
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505517
173
19760
T22
K
N
M
R
F
L
I
T
H
N
P
T
N
A
T
Chicken
Gallus gallus
XP_001231579
173
19729
T22
K
N
M
R
F
L
I
T
H
N
P
T
N
A
T
Frog
Xenopus laevis
NP_001085253
173
19738
T22
K
N
M
R
F
L
I
T
H
N
P
T
N
A
T
Zebra Danio
Brachydanio rerio
NP_998346
173
19839
T22
K
N
M
R
F
L
I
T
H
N
P
T
N
S
T
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
R17
K
N
P
Y
A
A
V
R
V
D
P
D
S
D
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
72.8
95.3
N.A.
96.5
78.6
N.A.
77.4
91.3
89.5
87.2
24.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
83.8
97.6
N.A.
98.2
87.8
N.A.
87.2
95.9
95.9
93.6
38.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
86.6
93.3
N.A.
93.3
93.3
93.3
86.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
100
N.A.
100
100
100
100
40
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
28
0
0
0
0
0
0
91
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
91
0
0
0
0
0
0
0
0
% I
% Lys:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
64
0
0
0
0
0
0
0
91
0
0
91
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
91
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
91
0
0
0
82
0
0
91
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _