KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROP1
All Species:
12.42
Human Site:
Y157
Identified Species:
30.37
UniProt:
O75360
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75360
NP_006252.2
226
24957
Y157
S
T
A
C
P
Y
S
Y
A
A
P
P
P
P
V
Chimpanzee
Pan troglodytes
XP_527140
226
24901
Y157
S
A
A
C
P
Y
S
Y
A
P
P
P
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001096271
540
59025
Y471
S
P
A
C
P
Y
S
Y
A
P
P
P
P
P
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97458
223
25007
Y154
S
S
A
Y
P
Y
T
Y
G
T
P
P
P
P
A
Rat
Rattus norvegicus
Q63087
326
36886
Q222
T
D
S
Y
P
Q
I
Q
N
N
L
W
A
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q0IH87
483
53526
Y365
S
R
H
G
F
S
S
Y
T
D
S
F
V
P
P
Zebra Danio
Brachydanio rerio
O42250
344
37854
I239
S
I
P
L
P
E
S
I
I
N
S
A
K
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06453
408
43639
F215
P
M
I
P
S
G
Y
F
N
Q
F
Q
R
A
P
Honey Bee
Apis mellifera
XP_624630
369
40270
H242
T
L
P
N
P
F
A
H
L
S
T
F
A
L
R
Nematode Worm
Caenorhab. elegans
NP_505519
264
29343
R177
M
Y
P
A
A
L
N
R
D
G
F
W
Y
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
31.2
N.A.
N.A.
72.5
27.2
N.A.
N.A.
N.A.
24.8
26.7
N.A.
25.7
30
27.2
N.A.
Protein Similarity:
100
98.6
35
N.A.
N.A.
77.8
40.7
N.A.
N.A.
N.A.
30.8
36.6
N.A.
34
38.4
44.3
N.A.
P-Site Identity:
100
86.6
86.6
N.A.
N.A.
60
6.6
N.A.
N.A.
N.A.
26.6
20
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
86.6
86.6
N.A.
N.A.
73.3
20
N.A.
N.A.
N.A.
26.6
20
N.A.
6.6
40
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
40
10
10
0
10
0
30
10
0
10
20
10
10
% A
% Cys:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
10
0
10
0
0
20
20
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
10
0
0
0
10
10
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
10
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
10
0
10
0
0
10
0
10
0
0
10
0
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
20
20
0
0
0
0
10
% N
% Pro:
10
10
30
10
70
0
0
0
0
20
40
40
40
50
20
% P
% Gln:
0
0
0
0
0
10
0
10
0
10
0
10
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
10
% R
% Ser:
60
10
10
0
10
10
50
0
0
10
20
0
0
10
10
% S
% Thr:
20
10
0
0
0
0
10
0
10
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
10
0
20
0
40
10
50
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _