KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD6
All Species:
0.3
Human Site:
Y15
Identified Species:
0.67
UniProt:
O75354
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75354
NP_001107561.1
484
53247
Y15
E
T
S
R
K
T
S
Y
I
F
Q
Q
P
Q
H
Chimpanzee
Pan troglodytes
XP_514557
623
67364
A154
S
P
W
V
W
R
S
A
R
C
T
Q
P
Q
H
Rhesus Macaque
Macaca mulatta
XP_001099807
472
51838
R16
Q
H
G
P
W
Q
T
R
M
R
K
I
S
N
H
Dog
Lupus familis
XP_542683
658
71395
R190
I
P
S
A
E
G
R
R
G
L
Q
A
A
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ9
427
47083
Rat
Rattus norvegicus
Q9ER31
455
49881
T13
N
H
G
T
L
R
M
T
K
V
A
Y
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518066
149
16186
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089154
468
52036
G16
E
Q
A
E
W
G
T
G
A
N
V
P
A
H
K
Zebra Danio
Brachydanio rerio
NP_001017862
442
49265
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XU84
479
53825
L16
L
L
I
S
F
F
S
L
L
S
V
V
T
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32621
518
56803
I21
A
F
A
V
I
M
L
I
L
L
I
K
T
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
94
62.3
N.A.
45.8
81.8
N.A.
24.7
N.A.
52.6
50.8
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
100
77.3
95
67.7
N.A.
59.7
86.9
N.A.
27.4
N.A.
67.9
64.4
N.A.
N.A.
N.A.
48.7
N.A.
P-Site Identity:
100
33.3
6.6
13.3
N.A.
0
6.6
N.A.
0
N.A.
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
33.3
20
N.A.
0
6.6
N.A.
0
N.A.
20
0
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
10
0
0
0
10
10
0
10
10
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
10
10
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
19
0
0
19
0
10
10
0
0
0
0
0
10
% G
% His:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
28
% H
% Ile:
10
0
10
0
10
0
0
10
10
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
10
0
10
10
0
0
19
% K
% Leu:
10
10
0
0
10
0
10
10
19
19
0
0
0
10
0
% L
% Met:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
19
0
10
0
0
0
0
0
0
0
10
28
0
0
% P
% Gln:
10
10
0
0
0
10
0
0
0
0
19
19
0
19
10
% Q
% Arg:
0
0
0
10
0
19
10
19
10
10
0
0
0
0
0
% R
% Ser:
10
0
19
10
0
0
28
0
0
10
0
0
10
10
10
% S
% Thr:
0
10
0
10
0
10
19
10
0
0
10
0
19
19
0
% T
% Val:
0
0
0
19
0
0
0
0
0
10
19
10
0
0
0
% V
% Trp:
0
0
10
0
28
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _