KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD6
All Species:
13.22
Human Site:
S481
Identified Species:
29.09
UniProt:
O75354
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75354
NP_001107561.1
484
53247
S481
D
S
L
N
R
Q
K
S
P
A
S
_
_
_
_
Chimpanzee
Pan troglodytes
XP_514557
623
67364
S620
D
S
L
N
R
Q
K
S
P
A
S
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001099807
472
51838
S469
D
S
L
N
R
Q
K
S
P
A
S
_
_
_
_
Dog
Lupus familis
XP_542683
658
71395
S655
D
S
L
N
R
Q
K
S
P
A
L
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ9
427
47083
Rat
Rattus norvegicus
Q9ER31
455
49881
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518066
149
16186
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089154
468
52036
K465
Y
Y
T
S
I
L
N
K
Q
H
S
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001017862
442
49265
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XU84
479
53825
N475
N
Q
V
L
S
Y
F
N
I
I
S
V
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32621
518
56803
K514
K
A
D
N
W
K
C
K
I
Q
S
A
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
94
62.3
N.A.
45.8
81.8
N.A.
24.7
N.A.
52.6
50.8
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
100
77.3
95
67.7
N.A.
59.7
86.9
N.A.
27.4
N.A.
67.9
64.4
N.A.
N.A.
N.A.
48.7
N.A.
P-Site Identity:
100
100
100
90.9
N.A.
0
0
N.A.
0
N.A.
9
0
N.A.
N.A.
N.A.
8.3
N.A.
P-Site Similarity:
100
100
100
90.9
N.A.
0
0
N.A.
0
N.A.
18.1
0
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
16.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
37
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
37
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
19
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
37
19
0
0
0
0
0
0
0
% K
% Leu:
0
0
37
10
0
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
46
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
37
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
37
0
10
10
0
0
37
0
0
55
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
46
64
64
64
% _