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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD6
All Species:
12.12
Human Site:
S426
Identified Species:
26.67
UniProt:
O75354
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75354
NP_001107561.1
484
53247
S426
L
E
T
Q
P
Q
S
S
P
F
S
C
M
D
L
Chimpanzee
Pan troglodytes
XP_514557
623
67364
S565
L
E
T
Q
P
Q
S
S
P
F
A
C
M
D
L
Rhesus Macaque
Macaca mulatta
XP_001099807
472
51838
S414
L
E
T
Q
P
Q
S
S
P
F
A
C
M
D
L
Dog
Lupus familis
XP_542683
658
71395
N600
A
E
T
R
P
Q
G
N
P
F
L
C
M
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ9
427
47083
S370
D
N
L
G
S
F
S
S
G
S
P
F
L
C
M
Rat
Rattus norvegicus
Q9ER31
455
49881
P398
E
T
Q
P
P
S
S
P
F
A
C
M
D
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518066
149
16186
S92
N
S
T
Y
K
L
Y
S
Y
S
Y
L
G
L
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089154
468
52036
P410
C
K
L
I
E
E
A
P
G
E
N
P
F
L
C
Zebra Danio
Brachydanio rerio
NP_001017862
442
49265
E385
M
S
A
G
G
I
K
E
S
P
F
L
C
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XU84
479
53825
M420
L
A
K
K
I
K
G
M
E
V
S
W
G
Q
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32621
518
56803
S459
L
D
E
L
E
S
D
S
H
F
C
L
D
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
94
62.3
N.A.
45.8
81.8
N.A.
24.7
N.A.
52.6
50.8
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
100
77.3
95
67.7
N.A.
59.7
86.9
N.A.
27.4
N.A.
67.9
64.4
N.A.
N.A.
N.A.
48.7
N.A.
P-Site Identity:
100
93.3
93.3
66.6
N.A.
13.3
13.3
N.A.
13.3
N.A.
0
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
26.6
13.3
N.A.
13.3
N.A.
26.6
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
10
0
0
10
19
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
19
37
10
10
10
% C
% Asp:
10
10
0
0
0
0
10
0
0
0
0
0
19
37
10
% D
% Glu:
10
37
10
0
19
10
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
46
10
10
10
0
0
% F
% Gly:
0
0
0
19
10
0
19
0
19
0
0
0
19
0
19
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
10
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
46
0
19
10
0
10
0
0
0
0
10
28
10
46
37
% L
% Met:
10
0
0
0
0
0
0
10
0
0
0
10
37
0
10
% M
% Asn:
10
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
10
46
0
0
19
37
10
10
10
0
0
0
% P
% Gln:
0
0
10
28
0
37
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
10
19
46
55
10
19
19
0
0
0
10
% S
% Thr:
0
10
46
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _