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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD6
All Species:
7.88
Human Site:
S327
Identified Species:
17.33
UniProt:
O75354
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75354
NP_001107561.1
484
53247
S327
E
L
V
S
P
C
L
S
P
S
F
K
G
E
W
Chimpanzee
Pan troglodytes
XP_514557
623
67364
S466
E
L
V
S
P
C
L
S
P
S
F
K
G
E
W
Rhesus Macaque
Macaca mulatta
XP_001099807
472
51838
S315
S
L
P
L
P
L
L
S
P
S
F
K
G
E
W
Dog
Lupus familis
XP_542683
658
71395
L501
K
E
L
V
S
P
C
L
S
P
G
F
T
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ9
427
47083
L272
H
T
F
R
S
A
C
L
P
R
W
L
E
A
E
Rat
Rattus norvegicus
Q9ER31
455
49881
P300
L
V
S
P
C
L
S
P
R
F
R
G
K
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518066
149
16186
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089154
468
52036
L308
S
L
Q
E
G
E
Q
L
V
T
S
C
L
T
P
Zebra Danio
Brachydanio rerio
NP_001017862
442
49265
A286
E
L
V
S
P
C
L
A
P
D
Y
S
G
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XU84
479
53825
E308
G
S
S
S
H
S
F
E
S
C
Y
G
T
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32621
518
56803
P331
Q
L
S
S
P
C
L
P
P
K
V
N
A
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
94
62.3
N.A.
45.8
81.8
N.A.
24.7
N.A.
52.6
50.8
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
100
77.3
95
67.7
N.A.
59.7
86.9
N.A.
27.4
N.A.
67.9
64.4
N.A.
N.A.
N.A.
48.7
N.A.
P-Site Identity:
100
100
73.3
0
N.A.
6.6
0
N.A.
0
N.A.
6.6
66.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
73.3
13.3
N.A.
13.3
6.6
N.A.
0
N.A.
13.3
86.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
10
37
19
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
28
10
0
10
0
10
0
10
0
0
0
0
10
28
28
% E
% Phe:
0
0
10
0
0
0
10
0
0
10
28
10
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
10
19
37
10
0
% G
% His:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
10
0
28
10
0
10
% K
% Leu:
10
55
10
10
0
19
46
28
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% N
% Pro:
0
0
10
10
46
10
0
19
55
10
0
0
0
0
10
% P
% Gln:
10
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
10
10
10
0
0
0
0
% R
% Ser:
19
10
28
46
19
10
10
28
19
28
10
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
19
28
0
% T
% Val:
0
10
28
10
0
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
37
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _