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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4B
All Species:
17.27
Human Site:
T322
Identified Species:
29.23
UniProt:
O75351
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75351
NP_004860.2
444
49302
T322
G
T
T
Q
N
S
L
T
E
A
D
F
R
E
L
Chimpanzee
Pan troglodytes
XP_001146376
412
45621
I288
P
W
V
L
D
S
A
I
R
R
R
F
E
K
R
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
T394
G
S
T
P
H
N
L
T
D
A
N
I
H
E
L
Dog
Lupus familis
XP_848812
444
49189
A322
G
T
T
Q
N
S
L
A
E
T
D
F
R
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P46467
444
49401
T322
G
S
T
Q
N
S
L
T
E
A
D
F
Q
E
L
Rat
Rattus norvegicus
Q5XIK7
488
55183
P359
V
L
A
A
T
N
F
P
W
D
I
D
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S362
G
N
T
P
H
S
L
S
E
A
N
I
H
E
L
Chicken
Gallus gallus
Q1HGK7
492
56020
D367
T
N
F
P
W
D
I
D
E
A
L
R
R
R
L
Frog
Xenopus laevis
Q9PUL2
486
55412
D345
G
G
A
S
E
N
E
D
P
S
K
M
V
M
V
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
D361
A
A
T
N
F
P
W
D
I
D
E
A
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393250
441
49311
T319
G
S
T
S
H
C
L
T
E
E
D
F
K
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
E372
V
S
G
P
S
A
G
E
E
S
S
K
M
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S356
G
S
G
E
H
E
S
S
R
R
V
K
S
E
L
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
N311
R
T
T
M
F
E
I
N
V
G
D
T
P
C
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
70.1
96.4
N.A.
95.5
35.2
N.A.
74.1
36.3
36.4
36.4
N.A.
N.A.
75.9
N.A.
34.8
Protein Similarity:
100
92.7
79
97.5
N.A.
97.3
54.9
N.A.
83.4
54.2
54.1
54.9
N.A.
N.A.
87.8
N.A.
53.1
P-Site Identity:
100
13.3
46.6
86.6
N.A.
86.6
6.6
N.A.
53.3
26.6
6.6
6.6
N.A.
N.A.
53.3
N.A.
6.6
P-Site Similarity:
100
26.6
80
86.6
N.A.
100
13.3
N.A.
73.3
33.3
26.6
13.3
N.A.
N.A.
80
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
61
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.1
74.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
0
8
8
8
0
36
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
8
0
22
8
15
36
8
0
0
0
% D
% Glu:
0
0
0
8
8
15
8
8
50
8
8
0
15
43
0
% E
% Phe:
0
0
8
0
15
0
8
0
0
0
0
36
0
0
0
% F
% Gly:
58
8
15
0
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
29
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
15
8
8
0
8
15
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
15
8
15
0
% K
% Leu:
0
8
0
8
0
0
43
0
0
0
8
0
8
0
65
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
8
% M
% Asn:
0
15
0
8
22
22
0
8
0
0
15
0
0
0
0
% N
% Pro:
8
0
0
29
0
8
0
8
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
22
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
15
15
8
8
22
15
15
% R
% Ser:
0
36
0
15
8
36
8
15
0
15
8
0
8
0
0
% S
% Thr:
8
22
58
0
8
0
0
29
0
8
0
8
0
0
0
% T
% Val:
15
0
8
0
0
0
0
0
8
0
8
0
8
8
15
% V
% Trp:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _