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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALOX12B
All Species:
20.91
Human Site:
S125
Identified Species:
46
UniProt:
O75342
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75342
NP_001130.1
701
80356
S125
G
K
T
T
A
D
D
S
L
P
V
L
L
E
H
Chimpanzee
Pan troglodytes
XP_511864
701
80411
S125
G
K
T
T
A
D
D
S
L
P
V
L
L
E
H
Rhesus Macaque
Macaca mulatta
XP_001111929
711
80558
S125
A
R
T
I
C
Q
D
S
L
P
L
L
L
D
H
Dog
Lupus familis
XP_546604
699
80232
T125
G
K
T
R
A
E
D
T
L
P
I
L
L
E
H
Cat
Felis silvestris
Mouse
Mus musculus
O70582
701
80559
T125
G
K
I
T
A
D
D
T
L
P
I
L
L
E
H
Rat
Rattus norvegicus
Q2KMM4
701
80722
T125
G
K
T
T
A
D
D
T
L
P
I
L
L
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517706
444
51126
Chicken
Gallus gallus
XP_423676
651
74206
D120
G
K
K
M
A
D
D
D
L
E
V
L
K
E
H
Frog
Xenopus laevis
NP_001089265
670
75862
G122
Q
G
K
G
I
I
L
G
D
S
V
S
P
V
I
Zebra Danio
Brachydanio rerio
NP_955912
670
76988
E122
G
T
A
K
K
L
S
E
D
S
L
P
L
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNR3
919
103708
P316
S
R
V
E
K
P
L
P
M
Y
V
P
R
D
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54.2
88.1
N.A.
86
86.5
N.A.
44
47.5
44.9
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
72.2
96
N.A.
94
94.1
N.A.
51
64.7
64.3
59
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
73.3
N.A.
80
86.6
N.A.
0
66.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
93.3
N.A.
93.3
100
N.A.
0
66.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
55
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
46
64
10
19
0
0
0
0
19
0
% D
% Glu:
0
0
0
10
0
10
0
10
0
10
0
0
0
64
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
64
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% H
% Ile:
0
0
10
10
10
10
0
0
0
0
28
0
0
0
10
% I
% Lys:
0
55
19
10
19
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
19
0
64
0
19
64
64
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
55
0
19
10
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
10
28
0
19
0
10
0
0
0
% S
% Thr:
0
10
46
37
0
0
0
28
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
46
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _