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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP12
All Species:
50.61
Human Site:
Y362
Identified Species:
92.78
UniProt:
O75317
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75317
NP_872294.1
370
42858
Y362
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
Y665
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
Y467
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Dog
Lupus familis
XP_543159
370
42853
Y362
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
Y362
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519444
446
51141
Y438
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q52KZ6
370
42846
Y362
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Zebra Danio
Brachydanio rerio
A4FUN7
371
43008
Y363
S
K
N
S
E
S
G
Y
I
L
F
Y
Q
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625039
354
40655
Y344
Q
K
S
S
E
T
G
Y
I
L
F
Y
Q
S
I
Nematode Worm
Caenorhab. elegans
P34547
426
48259
Y399
Q
K
N
S
E
S
A
Y
I
L
F
Y
Q
A
R
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
Y356
Q
K
N
S
D
S
G
Y
I
L
F
Y
Q
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24454
371
42429
Y360
S
S
N
T
D
H
G
Y
I
L
F
Y
E
S
L
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
Y661
S
P
N
M
A
T
A
Y
V
L
F
Y
K
A
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.9
76
99.1
N.A.
98.3
N.A.
N.A.
79.1
N.A.
98.3
93.2
N.A.
N.A.
72.1
59.1
76.7
Protein Similarity:
100
54.9
77.4
100
N.A.
99.7
N.A.
N.A.
81.6
N.A.
99.4
97.5
N.A.
N.A.
81.3
70.6
86.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
73.3
80
80
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.4
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73.3
34
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
16
0
0
0
0
0
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
77
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
8
% I
% Lys:
0
85
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% R
% Ser:
77
8
8
85
0
77
0
0
0
0
0
0
0
77
0
% S
% Thr:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
100
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _