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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP5
All Species:
28.79
Human Site:
S1485
Identified Species:
57.58
UniProt:
O75197
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75197
NP_002326.2
1615
179145
S1485
V
T
G
A
S
S
S
S
S
S
S
T
K
A
T
Chimpanzee
Pan troglodytes
XP_508605
1701
188045
S1571
V
T
G
A
S
S
S
S
S
S
S
T
K
A
T
Rhesus Macaque
Macaca mulatta
XP_001117791
1209
134638
C1080
L
D
P
S
S
R
N
C
S
P
P
T
T
F
L
Dog
Lupus familis
XP_866872
1612
180302
S1473
V
T
G
A
S
S
S
S
S
S
S
T
K
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91VN0
1614
178879
S1484
V
T
G
A
S
S
S
S
S
S
S
T
K
A
T
Rat
Rattus norvegicus
Q9QYP1
1905
211861
C1697
P
E
G
A
E
G
R
C
S
E
R
D
A
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508455
1480
165692
S1339
V
T
G
A
S
S
S
S
S
S
S
T
K
G
T
Chicken
Gallus gallus
NP_001012915
1616
180864
S1486
V
T
G
A
S
S
S
S
S
S
S
T
K
A
T
Frog
Xenopus laevis
NP_001079163
1605
179641
S1475
V
T
G
A
S
S
S
S
S
S
S
T
K
A
T
Zebra Danio
Brachydanio rerio
XP_696943
1405
157848
S1276
A
S
S
S
S
S
S
S
T
K
G
A
F
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P98163
1984
219502
R1617
A
R
L
D
G
S
R
R
D
M
L
L
Q
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202408
1322
148003
N1193
N
Y
P
K
E
T
L
N
P
P
P
S
P
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
61.5
70
N.A.
93.9
28.4
N.A.
63.9
87.8
80.1
66.5
N.A.
20.3
N.A.
N.A.
41.6
Protein Similarity:
100
94.4
62.9
83.2
N.A.
96.4
43.3
N.A.
76.1
94
88.7
75.6
N.A.
34.8
N.A.
N.A.
54.9
P-Site Identity:
100
100
20
93.3
N.A.
100
20
N.A.
93.3
100
100
26.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
40
93.3
N.A.
100
20
N.A.
93.3
100
100
46.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
67
0
0
0
0
0
0
0
9
9
50
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
9
0
0
17
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
67
0
9
9
0
0
0
0
9
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
9
0
0
59
0
0
% K
% Leu:
9
0
9
0
0
0
9
0
0
0
9
9
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
17
0
0
0
0
0
9
17
17
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% Q
% Arg:
0
9
0
0
0
9
17
9
0
0
9
0
0
9
0
% R
% Ser:
0
9
9
17
75
75
67
67
75
59
59
9
0
0
9
% S
% Thr:
0
59
0
0
0
9
0
0
9
0
0
67
9
0
67
% T
% Val:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _