KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP5
All Species:
18.79
Human Site:
S1462
Identified Species:
37.58
UniProt:
O75197
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75197
NP_002326.2
1615
179145
S1462
K
S
M
M
S
S
V
S
L
M
G
G
R
G
G
Chimpanzee
Pan troglodytes
XP_508605
1701
188045
S1548
K
S
M
M
S
S
V
S
L
M
G
G
R
G
G
Rhesus Macaque
Macaca mulatta
XP_001117791
1209
134638
L1057
G
Q
C
G
Q
L
C
L
A
I
P
G
G
H
R
Dog
Lupus familis
XP_866872
1612
180302
L1450
G
K
S
M
I
S
S
L
S
I
M
G
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91VN0
1614
178879
S1461
K
S
V
M
S
S
M
S
L
V
G
G
R
G
S
Rat
Rattus norvegicus
Q9QYP1
1905
211861
T1674
K
S
P
V
L
P
N
T
L
P
T
T
L
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508455
1480
165692
L1316
G
K
S
V
I
S
S
L
S
I
M
G
G
S
S
Chicken
Gallus gallus
NP_001012915
1616
180864
S1463
K
S
M
I
S
S
M
S
L
M
G
G
S
S
G
Frog
Xenopus laevis
NP_001079163
1605
179641
S1452
K
P
M
I
G
S
M
S
I
M
G
G
S
S
G
Zebra Danio
Brachydanio rerio
XP_696943
1405
157848
S1253
S
S
V
S
L
M
G
S
S
S
S
G
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P98163
1984
219502
V1594
H
A
R
I
F
Y
I
V
I
R
T
E
G
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202408
1322
148003
G1170
Y
E
R
N
L
P
T
G
A
S
S
C
S
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
61.5
70
N.A.
93.9
28.4
N.A.
63.9
87.8
80.1
66.5
N.A.
20.3
N.A.
N.A.
41.6
Protein Similarity:
100
94.4
62.9
83.2
N.A.
96.4
43.3
N.A.
76.1
94
88.7
75.6
N.A.
34.8
N.A.
N.A.
54.9
P-Site Identity:
100
100
6.6
20
N.A.
73.3
20
N.A.
13.3
73.3
53.3
20
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
13.3
26.6
N.A.
93.3
33.3
N.A.
26.6
86.6
73.3
26.6
N.A.
33.3
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
17
0
0
0
9
0
0
% A
% Cys:
0
0
9
0
0
0
9
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
0
0
9
9
0
9
9
0
0
42
75
34
25
42
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% H
% Ile:
0
0
0
25
17
0
9
0
17
25
0
0
0
0
0
% I
% Lys:
50
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
25
9
0
25
42
0
0
0
9
0
9
% L
% Met:
0
0
34
34
0
9
25
0
0
34
17
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
0
17
0
0
0
9
9
0
0
9
0
% P
% Gln:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
0
0
9
0
0
25
0
9
% R
% Ser:
9
50
17
9
34
59
17
50
25
17
17
0
25
42
34
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
17
9
0
0
0
% T
% Val:
0
0
17
17
0
0
17
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _