KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C2
All Species:
19.09
Human Site:
Y519
Identified Species:
35
UniProt:
O75185
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75185
NP_055676.2
946
103187
Y519
A
L
E
E
V
I
R
Y
C
T
M
Y
N
N
G
Chimpanzee
Pan troglodytes
XP_511142
1080
117831
Y653
A
L
E
E
V
I
R
Y
C
T
M
Y
N
N
G
Rhesus Macaque
Macaca mulatta
XP_001112571
947
103322
Y520
A
L
E
E
V
I
R
Y
C
T
M
Y
N
N
G
Dog
Lupus familis
XP_536762
921
100381
Y494
A
F
E
E
V
I
N
Y
C
T
M
Y
N
N
G
Cat
Felis silvestris
Mouse
Mus musculus
A7L9Z8
944
102509
H517
A
F
E
E
V
I
H
H
C
S
M
Y
N
N
G
Rat
Rattus norvegicus
Q8R4C1
944
103002
H517
A
F
E
E
V
I
H
H
C
S
T
Y
N
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509562
925
100997
Y498
A
F
E
E
V
I
R
Y
C
T
M
Y
N
N
G
Chicken
Gallus gallus
Q9YGL9
1042
115411
R524
A
P
E
S
V
I
E
R
C
T
H
V
R
V
G
Frog
Xenopus laevis
NP_001089971
916
100146
H490
L
F
E
E
V
I
Q
H
C
T
M
Y
N
S
G
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
F496
A
Y
E
Q
V
I
R
F
C
T
S
Y
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
A503
S
Y
C
T
P
L
K
A
S
R
L
G
T
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
S497
T
R
D
R
K
M
M
S
V
L
C
S
H
K
Q
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
S511
F
E
R
I
L
E
Y
S
T
S
Y
L
K
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
93.6
86.3
N.A.
84.5
84.7
N.A.
85.7
32
73.3
62.4
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.1
96
91.4
N.A.
91.8
92.8
N.A.
92.1
50.2
84
77.8
N.A.
52.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
93.3
46.6
66.6
60
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
80
N.A.
93.3
46.6
86.6
80
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
77
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
77
62
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
39
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
70
% G
% His:
0
0
0
0
0
0
16
24
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
8
0
77
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
0
0
0
8
8
16
% K
% Leu:
8
24
0
0
8
8
0
0
0
8
8
8
0
0
0
% L
% Met:
0
0
0
0
0
8
8
0
0
0
54
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
70
54
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
8
8
0
0
39
8
0
8
0
0
8
0
0
% R
% Ser:
8
0
0
8
0
0
0
16
8
24
8
8
0
24
0
% S
% Thr:
8
0
0
8
0
0
0
0
8
62
8
0
8
0
0
% T
% Val:
0
0
0
0
77
0
0
0
8
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
0
0
8
39
0
0
8
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _