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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C2
All Species:
9.7
Human Site:
Y22
Identified Species:
17.78
UniProt:
O75185
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75185
NP_055676.2
946
103187
Y22
F
S
G
G
G
R
Q
Y
Q
A
L
E
K
D
E
Chimpanzee
Pan troglodytes
XP_511142
1080
117831
Y156
F
S
G
G
G
C
Q
Y
Q
A
L
E
K
D
E
Rhesus Macaque
Macaca mulatta
XP_001112571
947
103322
Y22
F
S
G
G
G
R
Q
Y
Q
A
L
E
K
E
E
Dog
Lupus familis
XP_536762
921
100381
E22
S
G
A
G
H
L
Y
E
P
L
E
R
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
A7L9Z8
944
102509
L23
Q
N
H
R
Y
K
A
L
E
R
D
E
V
E
T
Rat
Rattus norvegicus
Q8R4C1
944
103002
L23
Q
N
H
R
Y
K
A
L
E
R
D
E
V
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509562
925
100997
K26
L
K
A
I
E
R
E
K
A
V
V
A
L
P
P
Chicken
Gallus gallus
Q9YGL9
1042
115411
C22
R
F
G
V
A
E
S
C
G
L
S
P
E
Q
V
Frog
Xenopus laevis
NP_001089971
916
100146
A23
D
E
V
V
P
I
P
A
K
E
A
S
R
L
S
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
E22
C
Q
P
D
S
K
D
E
T
M
V
P
V
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
R22
F
F
G
T
D
P
E
R
G
L
T
L
D
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
K22
F
F
G
V
D
P
T
K
G
L
S
D
S
Q
V
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
S30
D
A
T
A
E
A
L
S
K
P
S
P
S
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
93.6
86.3
N.A.
84.5
84.7
N.A.
85.7
32
73.3
62.4
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.1
96
91.4
N.A.
91.8
92.8
N.A.
92.1
50.2
84
77.8
N.A.
52.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
6.6
13.3
N.A.
6.6
6.6
0
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
13.3
N.A.
33.3
33.3
N.A.
20
13.3
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
8
8
16
8
8
24
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
16
0
8
0
0
0
16
8
8
24
0
% D
% Glu:
0
8
0
0
16
8
16
16
16
8
8
39
8
24
31
% E
% Phe:
39
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
47
31
24
0
0
0
24
0
0
0
0
0
0
% G
% His:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
24
0
16
16
0
0
0
24
0
0
% K
% Leu:
8
0
0
0
0
8
8
16
0
31
24
8
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
16
8
0
8
8
0
24
0
8
8
% P
% Gln:
16
8
0
0
0
0
24
0
24
0
0
0
0
24
0
% Q
% Arg:
8
0
0
16
0
24
0
8
0
16
0
8
8
0
0
% R
% Ser:
8
24
0
0
8
0
8
8
0
0
24
8
24
0
8
% S
% Thr:
0
0
8
8
0
0
8
0
8
0
8
0
0
0
24
% T
% Val:
0
0
8
24
0
0
0
0
0
8
16
0
24
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
8
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _