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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C2
All Species:
10.3
Human Site:
S38
Identified Species:
18.89
UniProt:
O75185
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75185
NP_055676.2
946
103187
S38
E
A
L
I
D
E
Q
S
E
L
K
A
I
E
K
Chimpanzee
Pan troglodytes
XP_511142
1080
117831
S172
E
A
L
I
D
E
Q
S
E
L
K
A
I
E
K
Rhesus Macaque
Macaca mulatta
XP_001112571
947
103322
S38
E
A
L
I
D
E
Q
S
E
L
K
A
I
E
K
Dog
Lupus familis
XP_536762
921
100381
S37
E
I
L
G
P
S
V
S
L
C
L
T
V
S
F
Cat
Felis silvestris
Mouse
Mus musculus
A7L9Z8
944
102509
K45
L
K
A
I
E
R
E
K
T
V
A
A
L
P
P
Rat
Rattus norvegicus
Q8R4C1
944
103002
E44
E
L
K
A
I
E
R
E
K
A
V
A
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509562
925
100997
K41
K
E
A
C
K
C
H
K
E
D
L
A
K
D
L
Chicken
Gallus gallus
Q9YGL9
1042
115411
G37
R
R
N
R
E
K
Y
G
P
N
E
L
P
A
E
Frog
Xenopus laevis
NP_001089971
916
100146
L38
A
N
E
L
V
K
Y
L
Q
V
D
L
E
S
G
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
V38
K
K
A
S
E
L
P
V
N
E
V
A
C
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
G37
K
A
N
Q
K
K
Y
G
P
N
E
L
P
T
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
R38
H
H
S
R
L
Y
G
R
N
V
L
P
E
E
K
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
E45
Y
C
T
L
S
V
D
E
A
L
E
K
L
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
93.6
86.3
N.A.
84.5
84.7
N.A.
85.7
32
73.3
62.4
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.1
96
91.4
N.A.
91.8
92.8
N.A.
92.1
50.2
84
77.8
N.A.
52.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
13.3
20
N.A.
13.3
0
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
40
33.3
N.A.
26.6
26.6
26.6
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
31
24
8
0
0
0
0
8
8
8
54
8
16
0
% A
% Cys:
0
8
0
8
0
8
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
0
24
0
8
0
0
8
8
0
0
16
0
% D
% Glu:
39
8
8
0
24
31
8
16
31
8
24
0
16
31
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
8
16
0
0
0
0
0
0
8
% G
% His:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
31
8
0
0
0
0
0
0
0
24
0
0
% I
% Lys:
24
16
8
0
16
24
0
16
8
0
24
8
8
0
31
% K
% Leu:
8
8
31
16
8
8
0
8
8
31
24
24
16
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
16
0
0
0
0
0
16
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
16
0
0
8
16
8
16
% P
% Gln:
0
0
0
8
0
0
24
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
0
16
0
8
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
8
0
31
0
0
0
0
0
16
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
0
0
8
0
8
8
% T
% Val:
0
0
0
0
8
8
8
8
0
24
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
24
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _