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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHACTR2
All Species:
9.7
Human Site:
S277
Identified Species:
21.33
UniProt:
O75167
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75167
NP_001093634.1
634
69700
S277
T
D
K
Q
P
I
T
S
H
L
S
S
D
T
T
Chimpanzee
Pan troglodytes
XP_001172467
634
69589
S277
T
G
K
Q
P
M
T
S
R
L
S
S
D
T
T
Rhesus Macaque
Macaca mulatta
XP_001090338
645
70506
S288
T
G
K
Q
P
T
T
S
R
L
S
S
D
T
T
Dog
Lupus familis
XP_533434
796
86705
S441
K
T
G
K
Q
P
T
S
R
S
S
S
D
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q501J7
694
76613
P338
I
P
P
S
S
P
S
P
P
L
P
T
H
I
P
Rat
Rattus norvegicus
P62025
569
62183
L228
T
S
S
L
K
G
E
L
S
D
T
G
V
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507077
582
62321
Q241
N
A
K
T
P
S
K
Q
P
P
V
P
P
P
K
Chicken
Gallus gallus
Q801X6
501
56077
P160
P
G
A
P
V
K
L
P
C
M
P
V
K
L
S
Frog
Xenopus laevis
Q5HZA1
694
76348
K338
S
T
D
A
V
T
N
K
E
N
A
L
G
P
A
Zebra Danio
Brachydanio rerio
Q6PEI3
754
84166
K389
P
S
P
P
M
P
P
K
R
T
T
P
V
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53858
892
100571
N311
P
K
P
V
I
G
N
N
S
V
T
N
E
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
94.2
70.3
N.A.
38.9
71.2
N.A.
48.1
35
39.3
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95.6
73.1
N.A.
52.3
76.5
N.A.
59.4
47.7
54.1
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
80
40
N.A.
6.6
6.6
N.A.
13.3
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
80
46.6
N.A.
20
20
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
0
0
0
0
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
10
0
0
37
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
10
0
0
19
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
10
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
10
37
10
10
10
10
19
0
0
0
0
10
10
19
% K
% Leu:
0
0
0
10
0
0
10
10
0
37
0
10
0
10
0
% L
% Met:
0
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
19
10
0
10
0
10
0
0
10
% N
% Pro:
28
10
28
19
37
28
10
19
19
10
19
19
10
19
10
% P
% Gln:
0
0
0
28
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% R
% Ser:
10
19
10
10
10
10
10
37
19
10
37
37
0
0
19
% S
% Thr:
37
19
0
10
0
19
37
0
0
10
28
10
0
37
37
% T
% Val:
0
0
0
10
19
0
0
0
0
10
10
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _