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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP4
All Species:
11.21
Human Site:
T893
Identified Species:
61.67
UniProt:
O75161
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75161
NP_055917.1
1426
157598
T893
E
L
A
A
M
L
L
T
H
A
R
Q
G
K
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P59240
1425
157194
T892
E
L
A
A
M
L
L
T
H
T
R
A
G
Q
G
Rat
Rattus norvegicus
NP_001032739
1428
158199
T895
E
L
A
A
M
L
L
T
H
T
R
A
G
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511323
1369
152550
S836
E
L
A
A
M
L
F
S
H
M
Q
E
G
N
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505982
1305
148655
A798
P
H
S
Y
R
I
H
A
K
P
L
P
G
N
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
78.4
77.4
N.A.
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
85.9
85.7
N.A.
74
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
80
80
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
80
0
0
0
20
0
20
0
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
80
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
60
% G
% His:
0
20
0
0
0
0
20
0
80
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
0
0
0
20
20
% K
% Leu:
0
80
0
0
0
80
60
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
80
0
0
0
0
20
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% N
% Pro:
20
0
0
0
0
0
0
0
0
20
0
20
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
20
0
40
0
% Q
% Arg:
0
0
0
0
20
0
0
0
0
0
60
0
0
0
0
% R
% Ser:
0
0
20
0
0
0
0
20
0
0
0
0
0
0
20
% S
% Thr:
0
0
0
0
0
0
0
60
0
40
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _