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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPHP4 All Species: 8.79
Human Site: S862 Identified Species: 48.33
UniProt: O75161 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75161 NP_055917.1 1426 157598 S862 A S R F S G G S L L T T G S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P59240 1425 157194 S861 A S F F S G G S L L I P G G P
Rat Rattus norvegicus NP_001032739 1428 158199 S864 A S F F S G G S L L I P G G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511323 1369 152550 S805 A S D F Q G G S L L S H S G H
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_505982 1305 148655 N768 S L T T T R S N V N S G Q G T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 78.4 77.4 N.A. 60.9 N.A. N.A. N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. 85.9 85.7 N.A. 74 N.A. N.A. N.A. N.A. N.A. N.A. 41.2 N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. 66.6 66.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 66.6 66.6 N.A. 60 N.A. N.A. N.A. N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 40 80 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 80 80 0 0 0 0 20 60 80 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 0 0 0 0 0 0 80 80 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 0 20 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 40 % P
% Gln: 0 0 0 0 20 0 0 0 0 0 0 0 20 0 0 % Q
% Arg: 0 0 20 0 0 20 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 80 0 0 60 0 20 80 0 0 40 0 20 20 20 % S
% Thr: 0 0 20 20 20 0 0 0 0 0 20 20 0 0 20 % T
% Val: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _