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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM23
All Species:
6.36
Human Site:
S59
Identified Species:
15.56
UniProt:
O75077
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75077
NP_003803.1
832
91926
S59
L
L
P
P
L
A
A
S
S
R
P
R
A
W
G
Chimpanzee
Pan troglodytes
XP_516049
775
86728
H17
R
R
I
Q
C
A
P
H
W
N
E
T
A
E
K
Rhesus Macaque
Macaca mulatta
XP_001106619
832
92267
S59
L
L
P
P
L
A
A
S
Y
R
P
R
A
W
G
Dog
Lupus familis
XP_849852
829
91876
S56
L
P
P
L
A
T
S
S
R
P
R
A
W
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1V7
829
91529
S56
L
P
A
L
A
T
S
S
R
P
R
A
R
G
A
Rat
Rattus norvegicus
Q9QYV0
816
88034
I56
V
V
Q
D
S
P
P
I
N
L
T
E
V
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508013
535
58857
Chicken
Gallus gallus
NP_001138702
758
84411
Frog
Xenopus laevis
O42596
935
104143
E60
L
R
L
I
F
S
N
E
E
D
N
Q
T
T
Q
Zebra Danio
Brachydanio rerio
XP_001923262
785
86613
V27
S
I
A
T
S
S
T
V
S
S
S
V
Q
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
96.3
94.7
N.A.
93.8
27.8
N.A.
58.6
72.3
42.8
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.4
97.4
97
N.A.
95.7
43.2
N.A.
60.8
81.8
54.9
74.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
20
N.A.
13.3
0
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
26.6
N.A.
20
20
N.A.
0
0
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
20
30
20
0
0
0
0
20
30
0
20
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
10
10
0
10
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
20
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
50
20
10
20
20
0
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
10
10
10
0
0
10
0
% N
% Pro:
0
20
30
20
0
10
20
0
0
20
20
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
10
10
0
20
% Q
% Arg:
10
20
0
0
0
0
0
0
20
20
20
20
10
0
0
% R
% Ser:
10
0
0
0
20
20
20
40
20
10
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
20
10
0
0
0
10
10
10
10
0
% T
% Val:
10
10
0
0
0
0
0
10
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
10
20
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _