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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKTN All Species: 40.91
Human Site: S439 Identified Species: 81.82
UniProt: O75072 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75072 NP_001073270.1 461 53724 S439 K T W D W K R S P P N V Q P N
Chimpanzee Pan troglodytes XP_001138798 461 53730 S439 K T W D W K R S P P N V Q P N
Rhesus Macaque Macaca mulatta XP_001109456 461 53725 S439 K T W D W K R S P P N V Q P N
Dog Lupus familis XP_538774 653 75081 S631 K T W D W K R S P P N V Q P N
Cat Felis silvestris
Mouse Mus musculus Q8R507 461 53560 S439 K T W D W K S S P P N V Q P N
Rat Rattus norvegicus NP_001102137 461 53449 S439 K T W D W K S S P P N V Q P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516116 461 53459 S439 K T W D W K S S P P N V Q P N
Chicken Gallus gallus XP_424885 543 62573 S521 K T W D W K N S P S N V Q Y N
Frog Xenopus laevis NP_001088460 460 54107 S438 K D W D W K N S P P N V Q P N
Zebra Danio Brachydanio rerio NP_001036159 457 52847 S435 K T W D W K T S P F N V Q E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09341 387 45117 N366 S W N S S G K N V K K N G K W
Sea Urchin Strong. purpuratus XP_790778 467 53912 S442 T Q W D W K E S P P N A R P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.4 66 N.A. 89.8 89.3 N.A. 75.6 61.6 65.7 56.6 N.A. N.A. N.A. 23.6 42.4
Protein Similarity: 100 99.5 99.1 68.7 N.A. 95 95.4 N.A. 88.5 72.9 78.5 71.3 N.A. N.A. N.A. 40.3 59.3
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 80 86.6 80 N.A. N.A. N.A. 0 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 80 86.6 80 N.A. N.A. N.A. 13.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 92 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 84 0 0 0 0 92 9 0 0 9 9 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 17 9 0 0 92 9 0 0 92 % N
% Pro: 0 0 0 0 0 0 0 0 92 75 0 0 0 75 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 84 0 0 % Q
% Arg: 0 0 0 0 0 0 34 0 0 0 0 0 9 0 0 % R
% Ser: 9 0 0 9 9 0 25 92 0 9 0 0 0 0 0 % S
% Thr: 9 75 0 0 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 84 0 0 0 % V
% Trp: 0 9 92 0 92 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _