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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KERA All Species: 30.3
Human Site: Y57 Identified Species: 74.07
UniProt: O60938 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60938 NP_008966.1 352 40509 Y57 P S F P T A L Y C E N R G L K
Chimpanzee Pan troglodytes XP_522489 352 40517 Y57 P N F P T A L Y C E N R G L K
Rhesus Macaque Macaca mulatta XP_001102581 352 40396 Y57 P S F P T A L Y C E N R G L K
Dog Lupus familis XP_539715 350 40304 Y57 P S F P T A L Y C E N R G L K
Cat Felis silvestris
Mouse Mus musculus O35367 351 40385 Y58 P S F P T A L Y C E N R G L T
Rat Rattus norvegicus Q9EQP5 377 43161 Y83 P D F P S A L Y C D S R N L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510956 352 40278 Y57 P N F P N A L Y C D S R G L K
Chicken Gallus gallus O42235 353 40247 Y58 P S F P N A L Y C D N K G L K
Frog Xenopus laevis Q9IB75 368 41179 C63 G L P P M D L C P F G C Q C H
Zebra Danio Brachydanio rerio NP_001020719 348 38920 N59 P N A V Y C D N K G L K S I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.3 92.6 N.A. 86 48.2 N.A. 83.8 69.6 27.7 56.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.7 96.5 N.A. 92.6 67.3 N.A. 90.3 83.2 45.9 69.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 93.3 60 N.A. 73.3 80 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 93.3 93.3 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 80 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 10 80 0 0 10 0 10 0 % C
% Asp: 0 10 0 0 0 10 10 0 0 30 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % E
% Phe: 0 0 80 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 10 10 0 70 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 20 0 0 60 % K
% Leu: 0 10 0 0 0 0 90 0 0 0 10 0 0 80 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 30 0 0 20 0 0 10 0 0 60 0 10 0 0 % N
% Pro: 90 0 10 90 0 0 0 0 10 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 10 % R
% Ser: 0 50 0 0 10 0 0 0 0 0 20 0 10 0 0 % S
% Thr: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _