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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KERA
All Species:
36.36
Human Site:
T275
Identified Species:
88.89
UniProt:
O60938
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60938
NP_008966.1
352
40509
T275
Q
L
S
H
N
Q
L
T
K
V
P
R
I
S
A
Chimpanzee
Pan troglodytes
XP_522489
352
40517
T275
Q
L
S
H
N
Q
L
T
K
V
P
R
I
S
A
Rhesus Macaque
Macaca mulatta
XP_001102581
352
40396
T275
Q
L
S
H
N
Q
L
T
K
V
P
R
I
S
A
Dog
Lupus familis
XP_539715
350
40304
T275
Q
L
S
H
N
Q
L
T
K
V
P
R
I
S
A
Cat
Felis silvestris
Mouse
Mus musculus
O35367
351
40385
T276
Q
L
S
Y
N
Q
L
T
N
F
P
R
I
N
A
Rat
Rattus norvegicus
Q9EQP5
377
43161
S299
H
L
S
H
N
K
I
S
N
V
P
A
I
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510956
352
40278
T275
Q
L
S
H
N
Q
L
T
K
V
P
R
I
S
P
Chicken
Gallus gallus
O42235
353
40247
T276
Q
L
S
H
N
Q
L
T
K
I
P
P
I
N
A
Frog
Xenopus laevis
Q9IB75
368
41179
S290
H
L
D
N
N
K
L
S
K
V
P
P
G
L
P
Zebra Danio
Brachydanio rerio
NP_001020719
348
38920
T274
Q
L
S
H
N
Q
L
T
E
V
P
V
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
92.6
N.A.
86
48.2
N.A.
83.8
69.6
27.7
56.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.7
96.5
N.A.
92.6
67.3
N.A.
90.3
83.2
45.9
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
53.3
N.A.
93.3
80
40
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
73.3
N.A.
93.3
93.3
60
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
20
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
90
0
0
% I
% Lys:
0
0
0
0
0
20
0
0
70
0
0
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
90
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
100
0
0
0
20
0
0
0
0
20
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
20
0
0
20
% P
% Gln:
80
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% R
% Ser:
0
0
90
0
0
0
0
20
0
0
0
0
0
70
10
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
80
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _