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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
29.09
Human Site:
S233
Identified Species:
53.33
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
S233
K
K
N
G
W
K
T
S
A
G
K
E
V
I
N
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
S233
K
K
N
G
W
K
T
S
A
G
K
E
V
I
N
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
S233
K
E
N
G
W
K
T
S
A
G
K
E
V
I
N
Dog
Lupus familis
XP_532858
285
31856
S232
K
K
N
G
W
K
T
S
T
G
K
E
V
I
N
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
S232
K
K
N
G
W
R
T
S
T
G
K
D
V
I
N
Rat
Rattus norvegicus
Q5BK46
285
31755
S232
K
K
N
G
W
R
T
S
T
G
K
D
V
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
S240
K
T
N
G
W
R
T
S
S
G
G
S
V
I
N
Frog
Xenopus laevis
NP_001084684
300
33514
S245
K
R
N
G
W
K
L
S
T
G
K
N
V
I
N
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
K223
K
S
N
G
W
R
L
K
S
G
G
V
I
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
K256
K
K
R
D
W
K
L
K
N
N
Q
P
V
K
N
Honey Bee
Apis mellifera
XP_395566
261
29754
I216
T
F
N
N
K
P
V
I
N
K
I
E
L
L
E
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
V206
S
E
V
L
N
Q
D
V
L
M
K
I
D
N
L
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
L189
D
V
I
N
K
E
D
L
V
K
L
D
K
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
N.A.
66.6
73.3
46.6
N.A.
40
13.3
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
66.6
N.A.
46.6
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
16
0
0
0
0
24
8
0
0
% D
% Glu:
0
16
0
0
0
8
0
0
0
0
0
39
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
0
0
70
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
8
8
8
70
0
% I
% Lys:
77
47
0
0
16
47
0
16
0
16
62
0
8
8
0
% K
% Leu:
0
0
0
8
0
0
24
8
8
0
8
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
77
16
8
0
0
0
16
8
0
8
0
8
85
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
8
0
0
31
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
62
16
0
0
8
0
0
0
% S
% Thr:
8
8
0
0
0
0
54
0
31
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
0
8
8
8
0
0
8
70
0
0
% V
% Trp:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _