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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDF1
All Species:
53.03
Human Site:
Y109
Identified Species:
83.33
UniProt:
O60869
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60869
NP_003783.1
148
16369
Y109
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Chimpanzee
Pan troglodytes
XP_001163031
156
17448
Y117
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Rhesus Macaque
Macaca mulatta
XP_001106825
148
16426
Y109
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Dog
Lupus familis
XP_537793
190
20933
Y151
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P69736
148
16350
Y109
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510092
151
16669
Y112
K
P
Q
V
I
A
D
Y
E
C
G
R
A
I
P
Chicken
Gallus gallus
Q5ZMC0
148
16345
Y109
K
P
Q
V
I
A
D
Y
E
S
G
R
A
I
P
Frog
Xenopus laevis
Q6GPQ6
147
16302
Y109
K
P
Q
V
I
A
D
Y
E
C
G
K
A
I
P
Zebra Danio
Brachydanio rerio
Q6PBY3
146
16056
Y108
K
P
Q
I
I
A
E
Y
E
C
G
K
A
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524110
145
16038
K129
M
E
R
V
L
G
I
K
L
R
G
K
E
R
G
Honey Bee
Apis mellifera
XP_623269
147
16256
Y108
K
A
Q
V
I
N
D
Y
E
A
G
R
G
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788121
145
16195
Y108
K
Q
Q
V
I
N
E
Y
E
S
G
K
A
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXT3
142
15563
Y115
K
P
Q
V
I
Q
E
Y
E
S
G
K
A
I
P
Baker's Yeast
Sacchar. cerevisiae
O14467
151
16385
Y113
K
P
T
V
V
N
D
Y
E
A
A
R
A
I
P
Red Bread Mold
Neurospora crassa
Q871W6
160
17161
Y121
T
Q
A
I
I
A
Q
Y
E
R
G
E
G
V
P
Conservation
Percent
Protein Identity:
100
82.6
94.5
77.8
N.A.
N.A.
98.6
N.A.
87.4
93.2
88.5
82.4
N.A.
63.5
64.8
N.A.
65.5
Protein Similarity:
100
87.8
97.3
77.8
N.A.
N.A.
100
N.A.
91.3
97.3
95.2
90.5
N.A.
79.7
77.6
N.A.
83.7
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
93.3
100
86.6
73.3
N.A.
13.3
73.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
93.3
100
93.3
93.3
N.A.
33.3
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
52
41.7
36.8
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
53.7
P-Site Identity:
N.A.
N.A.
N.A.
80
66.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
80
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
67
0
0
0
14
7
0
80
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
20
0
94
0
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
94
0
14
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
87
0
7
0
0
0
0
0
0
80
0
% I
% Lys:
87
0
0
0
0
0
0
7
0
0
0
34
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
74
0
0
0
0
0
0
0
0
0
0
0
0
87
% P
% Gln:
0
14
80
0
0
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
14
0
60
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
87
7
0
0
0
0
0
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _